Evidence map›Paper›PMID 36423940›Full record

ArticleBMJ case reports2022

Clinical heterogeneity in monogenic chylomicronaemia.

Britt E Heidemann, Remy H H Bemelmans, A David Marais, Frank L J Visseren, Charlotte Koopal

Open access · hybridAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Britt E HeidemannDepartment of Vascular Medicine, University Medical Center Utrecht, University Utrecht, Utrecht, The Netherlands.
Remy H H BemelmansDepartment of Internal Medicine, Ziekenhuis Gelderse Vallei, Ede, The Netherlands.
A David MaraisDivision of Chemical Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Frank L J VisserenDepartment of Vascular Medicine, University Medical Center Utrecht, University Utrecht, Utrecht, The Netherlands f.l.j.visseren@umcutrecht.nl.
Charlotte KoopalDepartment of Vascular Medicine, University Medical Center Utrecht, University Utrecht, Utrecht, The Netherlands.
University Medical Center Utrecht · NLUniversity of Cape Town · ZAUtrecht University · NLZiekenhuis Gelderse Vallei · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chylomicronaemia accompanies hypertriglyceridaemia, usually due to a polygenic predisposition in combination with secondary risk factors. Monogenic chylomicronaemia represents a small subgroup of patients with hypertriglyceridaemia. This article describes three patients and illustrates the heterogeneity in the presentation of monogenic chylomicronaemia. The first case is a man with mild hypertriglyceridaemia who is a compound heterozygote for two variants in the

Indexed as

HypertriglyceridemiaPancreatitisFemaleGenetic TestingGenotypeHomozygoteHumansMaleGeneticsLipid disordersPancreatitis

Identifiers

PMID36423940
PMCPMC9693862
OpenAlexW4309931025

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.