Evidence map›Paper›PMID 36423898›Full record

ArticleEuropean psychiatry : the journal of the Association of European Psychiatrists2022

The effectiveness of trauma-focused psychotherapy for complex post-traumatic stress disorder: A retrospective study.

Eirini Melegkovits, Jocelyn Blumberg, Emily Dixon, Kimberley Ehntholt, Julia Gillard, Hamodi Kayal, Tim Kember, Livia Ottisova, Eileen Walsh, Maximillian Wood and 5 more

Open access · goldAbstract read
In one paragraph

Article in European psychiatry : the journal of the Association of European Psychiatrists, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 2 countries.

Eirini MelegkovitsTraumatic Stress Clinic, Division of Psychiatry, University College London, London, United Kingdom.ORCID 0000-0002-4932-9152
Jocelyn BlumbergTraumatic Stress Clinic, St Pancras Hospital, Camden and Islington NHS Foundation Trust, London, United Kingdom.
Emily DixonTraumatic Stress Clinic, St Pancras Hospital, Camden and Islington NHS Foundation Trust, London, United Kingdom.
Kimberley EhntholtTraumatic Stress Clinic, St Pancras Hospital, Camden and Islington NHS Foundation Trust, London, United Kingdom.
Julia GillardTraumatic Stress Clinic, St Pancras Hospital, Camden and Islington NHS Foundation Trust, London, United Kingdom.ORCID 0000-0001-5520-1721
Hamodi KayalTraumatic Stress Clinic, St Pancras Hospital, Camden and Islington NHS Foundation Trust, London, United Kingdom.
Tim KemberTraumatic Stress Clinic, St Pancras Hospital, Camden and Islington NHS Foundation Trust, London, United Kingdom.
Livia OttisovaTraumatic Stress Clinic, St Pancras Hospital, Camden and Islington NHS Foundation Trust, London, United Kingdom.ORCID 0000-0002-0920-411X
Eileen WalshTraumatic Stress Clinic, St Pancras Hospital, Camden and Islington NHS Foundation Trust, London, United Kingdom.ORCID 0000-0001-6507-2222
Maximillian WoodTraumatic Stress Clinic, St Pancras Hospital, Camden and Islington NHS Foundation Trust, London, United Kingdom.
Rafael GafoorResearch Department of Primary Care and Population Health, UCL, Royal Free Hospital, London, United Kingdom.ORCID 0000-0001-6865-1270
Chris BrewinClinical, Educational and Health Psychology, University College London, London, United Kingdom.
Jo BillingsTraumatic Stress Clinic, Division of Psychiatry, University College London, London, United Kingdom.ORCID 0000-0003-1238-2440
Mary RobertsonTraumatic Stress Clinic, St Pancras Hospital, Camden and Islington NHS Foundation Trust, London, United Kingdom.
Michael BloomfieldTraumatic Stress Clinic, St Pancras Hospital, Camden and Islington NHS Foundation Trust, London, United Kingdom.
St Pancras Hospital · GBNational Center for Post Traumatic Stress Disorder · USCamden and Islington NHS Foundation Trust · GBThe Royal Free Hospital · GBUniversity College Hospital · GBUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe retrospectively evaluated the effectiveness of trauma-focused psychotherapy (TF-P) versus stabilization and waiting in a civilian cohort of patients with an 11th version of the international classification of disease (ICD-11) diagnosis of complex post-traumatic stress disorder (CPTSD).

methodsWe identified patients with CPTSD treated at a specialist trauma service over a 3-year period by triangulating evidence from self-report questionnaires, file review, and expert-clinician opinion. Patients completed a phase-based treatment: stabilization consisting of symptom management and establishing safety, followed by waiting for treatment (phase 1); individual TF-P in the form of trauma-focused cognitive behavioral therapy (TF-CBT), or eye movement desensitization and reprocessing (EMDR) or TF-CBT plus EMDR (phase 2). Our primary outcome was PTSD symptoms during phase 2 versus phase 1. Secondary outcomes included depressive symptoms, functional impairment, and a proxy CPTSD measure. Exploratory analysis compared outcomes between treatments. Adverse outcomes were recorded.

resultsFifty-nine patients were included. Compared to receiving only phase 1, patients completing TF-P showed statistically significant reductions in PTSD [

conclusionsThis study suggests that TF-P effectively improves symptoms of CPTSD. However, prospective research with validated measurements is necessary to evaluate current and new treatments and identify personal markers of treatment effectiveness for CPTSD.

Indexed as

Cognitive Behavioral TherapyStress Disorders, Post-TraumaticHumansProspective StudiesPsychotherapyRetrospective StudiesComplex post-traumatic stress disorderCPTSDEMDRICD-11trauma-focused CBT

Identifiers

PMID36423898
PMCPMC9879871
OpenAlexW4309907981

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.