Evidence map›Paper›PMID 36423798›Full record

ArticleJournal of pain and symptom management2023

How Important is Spirometry for Identifying Patients with COPD Appropriate for Palliative Care?

Allison V Lange, Anuj B Mehta, David B Bekelman

Open access · greenAbstract read
In one paragraph

Article in Journal of pain and symptom management, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 3 countries.

Allison V LangeDivision of Pulmonary Sciences and Critical Care Medicine, Department of Medicine (A.L., A.M.); University of Colorado Anschutz Medical Campus; Aurora, Colorado. Electronic address: Allison.lange@cuanschutz.edu.
Anuj B MehtaDivision of Pulmonary Sciences and Critical Care Medicine, Department of Medicine (A.L., A.M.); University of Colorado Anschutz Medical Campus; Aurora, Colorado; Division of Pulmonary and Critical Care Medicine, Department of Medicine (A.M.), Denver Health and Hospital Authority; Denver, Colorado.
David B BekelmanMedical Service (D.B.), Rocky Mountain Regional Veterans Affairs Medical Center; Aurora, Colorado; Denver-Seattle Center of Innovation (D.B.); Rocky Mountain Regional Veterans Affairs Medical Center; Aurora, Colorado; Division of General Internal Medicine, Department of Medicine (D.B.); University of Colorado Anschutz Medical Campus; Aurora, Colorado.
The Medical Center of Aurora · USUniversity of Colorado Hospital · US

Funding

MULTIDISCIPLINARY RESPIRATORY DISEASES RESEARCH TRAININGT32HL007085 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI ELLEN L BURNHAM, LISA A MAIER · 1985 to 2026
$21.6M
Institutional Career Development CoreKL2TR002534 · NCATS · UNIVERSITY OF COLORADO DENVER · PI BURNHAM, ELLEN L · 2018 to 2022
$4.6M
Mid-Career Mentoring Award in Palliative Care, Aging, and Cognitive ImpairmentK24AG070322 · NIA · UNIVERSITY OF COLORADO DENVER · PI David B. Bekelman · 2022 to 2026
$930k
HSRD VA I01 HX001770NCATS NIH HHS KL2 TR002534NIA NIH HHS K24 AG070322
6 · The paper itself

Abstract

backgroundProviding palliative care to patients with chronic obstructive pulmonary disease (COPD) is a priority. Spirometry demonstrating airflow limitation is a diagnostic test for COPD and a common inclusion criterion for palliative care research. However, requiring spirometry with airflow limitation may exclude appropriate patients unable to complete spirometry, or patients with preserved-ratio impaired spirometry and symptoms or imaging consistent with COPD. MEASURES: To determine differences in quality of life (QOL) and symptoms between patients with COPD identified based on International Classification of Diseases (ICD) codes and spirometry with airflow limitation compared to ICD codes only.

interventionPatients with COPD enrolled in a palliative care trial were included. Patients were at high risk of hospitalization and death and reported poor QOL. Baseline measures of QOL (Functional Assessment of Cancer Therapy-General (FACT-G), the Clinical COPD Questionnaire, and Quality of Life at the End of Life), and symptoms (Patient Health Questionnaire-8, Generalized Anxiety Disorder-7, fatigue, Insomnia Severity Index) were compared. OUTCOMES: Two hundred eight patients with COPD were predominantly male, White, and average age was 68.4. Between patients with ICD codes and spirometry with airflow limitation compared to patients with ICD codes only, there were no significant differences in FACT-G (59.0 vs. 55.0, P = 0.33), other measures of QOL, or symptoms between groups.

conclusionThese results imply that spirometry may not need to be a requirement for inclusion into palliative care research or clinical care for patients with poor quality of life and at high risk for adverse outcomes.

Indexed as

Pulmonary Disease, Chronic ObstructiveQuality of LifeAgedFemaleHospitalizationHumansMalePalliative CareSpirometryclinical trialCOPDpalliative carequality of life

Identifiers

PMID36423798
PMCPMC10998735
OpenAlexW4309535598

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.