Evidence map›Paper›PMID 36423583›Full record

ArticleUrologia internationalis2023

Perinephric Toxic Fat: Impact on Surgical Complexity, Perioperative Outcome, and Surgical Approach in Partial Nephrectomy.

Margarete Teresa Walach, Frank Schiefelbein, Andreas Schneller, Georg Schoen, Christoph A J von Klot, Olga Katzendorn, Julia Mühlbauer, Philipp Nuhn, Maximilian Christian Kriegmair, Nina Natascha Harke

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In one paragraph

Article in Urologia internationalis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Perirenal Fat in Disease Progression: From Inflammatory Mediator to Therapeutic Target.International journal of urology : official journal of the Japanese Urological Association · 2025
    Review
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  7. Article
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  10. Article
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  13. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Margarete Teresa WalachDepartment of Urology and Urologic Surgery, University Medical Center Mannheim, University of Heidelberg, Mannheim, Germany.
Frank SchiefelbeinDepartment of Urology, Klinikum Wuerzburg Mitte - Missioklinik, Wuerzburg, Germany.
Andreas SchnellerDepartment of Urology, Klinikum Wuerzburg Mitte - Missioklinik, Wuerzburg, Germany.
Georg SchoenDepartment of Urology, Urological Clinic Muenchen - Planegg, Planegg, Germany.
Christoph A J von KlotDepartment of Urology and Urologic Oncology, Hannover Medical School, Hannover, Germany.
Olga KatzendornDepartment of Urology and Urologic Oncology, Hannover Medical School, Hannover, Germany.
Julia MühlbauerDepartment of Urology and Urologic Surgery, University Medical Center Mannheim, University of Heidelberg, Mannheim, Germany.
Philipp NuhnDepartment of Urology and Urologic Surgery, University Medical Center Mannheim, University of Heidelberg, Mannheim, Germany.
Maximilian Christian KriegmairDepartment of Urology and Urologic Surgery, University Medical Center Mannheim, University of Heidelberg, Mannheim, Germany.
Nina Natascha HarkeDepartment of Urology and Urologic Oncology, Hannover Medical School, Hannover, Germany.
Heidelberg University · DEMedizinische Hochschule Hannover · DEKlinikum Würzburg Mitte · DEUrologische Klinik München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTo assess influencing factors on perinephric toxic fat (high Mayo Adhesive Probability [MAP] score) and the impact of high MAP scores on surgical complexity, perioperative outcome, and surgical approach in patients with localized renal tumors undergoing open (OPN) and robot-assisted partial nephrectomy (RAPN).

methods698 patients were included in this study. Based on preoperative imaging, adherent perinephric fat (APF) was assessed to define MAP scores. Regression analyses assessed influencing parameters for high MAP scores (≥3), predictors of surgical outcome, and influencing factors on surgical approach.

resultsOPN was performed in 331 (47%) patients, and 367 (53%) patients underwent RAPN. Male gender (p < 0.001), age ≥65 (p < 0.001), and BMI ≥27.4 kg/m2 (p < 0.001) showed to be significantly influencing factors for the presence of APF. High MAP scores showed to be an influencing factor for a prolonged surgery duration (OR = 1.68, 95% CI 1.22-2.31, p = 0.002) and a significant predictor to rather undergo OPN than RAPN (OR = 1.5, 95% CI 1.05-2.15, p = 0.027).

conclusionOlder, male patients with high BMI scores have a higher risk for APF. The presence of APF increases surgery time and may have an impact on decision making regarding the preferred surgical approach.

Indexed as

Kidney NeoplasmsRobotic Surgical ProceduresAdipose TissueHumansKidneyMaleNephrectomyRetrospective StudiesTreatment OutcomeAdhesive perinephric fatMayo adhesive probability scorePartial nephrectomyRenal cancerSurgical approach

Identifiers

PMID36423583
PMCPMC9945181
OpenAlexW4309905296

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.