Evidence map›Paper›PMID 36423578›Full record

ArticleCell2022

Bioactive metabolites: The double-edged sword in your food.

Jens Nielsen

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Cell, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Is Ergothioneine an Important Source of Plasma TrimethylamineAntioxidants (Basel, Switzerland) · 2026
    Article
  2. Ergothioneine Improves the Quality of Boar Sperm DuringAnimals : an open access journal from MDPI · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 2 countries.

Jens NielsenBioInnovation Institute, Ole Maaløes Vej 3, DK2200 Copenhagen N, Denmark; Department of Biology and Biological Engineering, Chalmers University of Technology, SE41296 Gothenburg, Sweden. Electronic address: nielsenj@chalmers.se.
BioInnovation Institute · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Food contains many different bioactive metabolites that interact with human metabolism. Many of these have health benefits, but in this issue of Cell, researchers show that the gut microbiome can convert a bioactive metabolite to metabolites that may elevate the risks of developing cardiovascular disease.

Indexed as

Cardiovascular DiseasesGastrointestinal MicrobiomeFoodHumans

Identifiers

PMID36423578
OpenAlexW4310020627

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.