Evidence map›Paper›PMID 36423153›Full record

ArticleViruses2022

Exploring the Public Health and Social Implications of Future Curative Hepatitis B Interventions.

Jack Wallace, Jacqueline Richmond, Jessica Howell, Behzad Hajarizadeh, Jennifer Power, Carla Treloar, Peter A Revill, Benjamin Cowie, Su Wang, Mark Stoové and 2 more

Abstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jack WallaceBurnet Institute, Melbourne, VIC 3004, Australia.ORCID 0000-0002-4738-7316
Jacqueline RichmondBurnet Institute, Melbourne, VIC 3004, Australia.
Jessica HowellBurnet Institute, Melbourne, VIC 3004, Australia.ORCID 0000-0002-9269-6249
Behzad HajarizadehThe Kirby Institute, UNSW, Sydney, NSW 3052, Australia.ORCID 0000-0003-2212-2028
Jennifer PowerAustralian Research Centre in Sex, Health and Society, Latrobe University, Bundoora, VIC 3083, Australia.
Carla TreloarCentre for Social Research in Health, UNSW, Sydney, NSW 2052, Australia.
Peter A RevillVictorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC 3010, Australia.ORCID 0000-0003-2715-2541
Benjamin CowieWHO Collaborating Centre for Viral Hepatitis, Peter Doherty Institute for Infection and Immunity, Parkville, VIC 3010, Australia.
Su WangCenter for Asian Health, Saint Barnabas Medical Center, RWJBarnabas-Rutgers Medical Group, Florham Park, NJ 07039, USA.
Mark StoovéBurnet Institute, Melbourne, VIC 3004, Australia.
Alisa PedranaBurnet Institute, Melbourne, VIC 3004, Australia.
Margaret HellardBurnet Institute, Melbourne, VIC 3004, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis B is a significant global health issue where the 296 million people estimated to live with the infection risk liver disease or cancer without clinical intervention. The World Health Organization has committed to eliminating viral hepatitis as a public health threat by 2030, with future curative hepatitis B interventions potentially revolutionizing public health responses to hepatitis B, and being essential for viral hepatitis elimination. Understanding the social and public health implications of any cure is imperative for its successful implementation. This exploratory research, using semi-structured qualitative interviews with a broad range of professional stakeholders identifies the public health elements needed to ensure that a hepatitis B cure can be accessed by all people with hepatitis B. Issues highlighted by the experience of hepatitis C cure access include preparatory work to reorientate policy settings, develop resourcing options, and the appropriateness of health service delivery models. While the form and complexity of curative hepatitis B interventions are to be determined, addressing current disparities in cascade of care figures is imperative with implementation models needing to respond to the cultural contexts, social implications, and health needs of people with hepatitis B, with cure endpoints and discourse being contested.

Indexed as

Hepatitis BHepatitis CHepatitis, Viral, HumanHepacivirusHumansPublic Healtheliminationhepatitis B curehepatitis B virusimplementationpublic healthsocial impactstigmatreatment

Identifiers

PMID36423153
PMCPMC9693003

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.