ArticleViruses2022
Clinical Epidemiology, Pathology, and Molecular Investigation of Lumpy Skin Disease Outbreaks in Bangladesh during 2020-2021 Indicate the Re-Emergence of an Old African Strain.
Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
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Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Lumpy Skin Disease in Cattle and Buffalo in Asian Countries: A Systematic Review and Meta-Analysis.Veterinary medicine and science · 2025Pooled it
- Lumpy skin disease: a systematic review of mode of transmission, risk of emergence, and risk entry pathways.Virus genes · 2025Pooled it
- The global scenario of lumpy skin disease, its epidemiological investigation, and prevalence in livestock: A review.Veterinary and animal science · 2026Review
- First Complete Genome Sequencing of a Pigeonpox Virus Strain from Mainland China and Preliminary Evaluation of Its Attenuated Potential.Veterinary sciences · 2026Article
- Diagnostic approach, vaccination and treatment priorities for Lumpy Skin Disease in cattle: lessons from Balkan epidemics to Western Europe re-emergence (2025).Veterinary research communications · 2026Review
- Demonstration of the pathogenicity of LSDV pendik strain in cattle.Archives of virology · 2026Article
- Lumpy Skin Disease Virus Infected Calves Showing Multisystemic Vasculitis on Postmortem Examination: A Summary of Six Cases.Transboundary and emerging diseases · 2026Article
- Spatial epidemiology of lumpy skin disease outbreaks in Thailand: proximity patterns, case concentrations, spatio-temporal clusters, and interpolated case distribution.Frontiers in veterinary science · 2026Article
- Retrospective analysis of genetic diversity, clinical manifestations and risk factors, during outbreak of lumpy skin disease virus.PloS one · 2026Article
- Review
- Global expansion of lumpy skin disease: transmission trends, economic consequences, and preventive measures.Veterinary research communications · 2025Review
- Article
- Development of a Multi-Locus Real-Time PCR with a High-Resolution Melting Assay to Differentiate Wild-Type, Asian Recombinant, and Vaccine Strains of Lumpy Skin Disease Virus.Veterinary sciences · 2025Article
- Lumpy skin disease: A growing threat to the global livestock industry.Open veterinary journal · 2025Review
- Characterization of Lumpy Skin Disease in Northern Bangladesh: Clinical, Pathological, Biochemical, and Molecular Perspectives.Veterinary medicine international · 2025Article
- Spatiotemporal Distribution and Meteorological Determinants of Lumpy Skin Disease (LSD) Occurrence in Bangladesh From 2020 to 2023.Transboundary and emerging diseases · 2025Article
- Serological response to lumpy skin disease in recovered and clinically healthy vaccinated and unvaccinated cattle of Bangladesh.Frontiers in veterinary science · 2025Article
- Investigating Transboundary Spread Patterns and Cluster Characteristics of Lumpy Skin Disease (LSD) Outbreaks in Asia: Levering the Outbreak Data (2019-2023) to Support the LSD Prevention and Control Strategies.Transboundary and emerging diseases · 2025Article
- Article
- Pathological, immunological and molecular epidemiological analysis of lumpy skin disease virus in Indian cattle during a high-mortality epidemic.The veterinary quarterly · 2024Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lumpy skin disease (LSD) emerged in Bangladesh in mid-2019, leading to great economic losses for cattle farmers. This study describes the recent occurrence of the LSDV in Bangladesh and examines the clinical manifestation of the disease in local cattle breeds, characteristic epidemiological features, and pathological findings in affected animals. In addition, a full-genome sequencing of two local LSDV isolates was carried out. A total of 565 animals from 88 households were investigated, and 165 samples (skin lesions, saliva, nasal discharge, feces, and milk) were collected for virus detection. Pathology and immunohistochemistry were performed on nodule biopsies. Fever, nodular skin lesions, and swelling of the joints were the most common clinical manifestations. Skin lesions had a higher concentration of viral DNA compared to other sample types and were therefore selected for virus isolation and characterization. Pathology of the LSD skin nodules comprised a granulomatous reaction in the dermis and hypodermis that extended to the surrounding tissues. Development of the skin lesions started with swelling of keratinocytes with cytoplasmic vacuolation, vasculitis, panniculitis, thrombosis, and infarction. Altogether, the LSDV produced transmural, hemorrhagic, necrotizing, proliferative and ulcerative dermatitis. The LSD viral antigen was detected occasionally in the macrophages, epithelial cells, and vascular smooth muscle cells. The complete genome sequence analysis revealed that the two Bangladeshi field strains (BD-V392.1 and BD-V395.1) were distinct from the contemporary field strains and were closely related to the ancestral African Neethling strain. The findings of this study will improve the diagnosis, monitoring, and control of LSD in Bangladesh.
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