Evidence map›Paper›PMID 36423116›Full record

ArticleViruses2022

Insights on 21 Years of HBV Surveillance in Blood Donors in France.

Pierre Cappy, Laure Boizeau, Daniel Candotti, Sophie Le Cam, Christophe Martinaud, Josiane Pillonel, Martin Tribout, Claude Maugard, Josiane Relave, Pascale Richard and 2 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Pierre CappyDepartment of Microbiology, Henri Mondor University Hospital, Assistance Publique-Hôpitaux de Paris, 94010 Créteil, France.ORCID 0000-0001-8540-2196
Laure BoizeauDepartment of Microbiology, Henri Mondor University Hospital, Assistance Publique-Hôpitaux de Paris, 94010 Créteil, France.
Daniel CandottiDepartment of Microbiology, Henri Mondor University Hospital, Assistance Publique-Hôpitaux de Paris, 94010 Créteil, France.
Sophie Le CamEtablissement Français du Sang (EFS), 93210 La Plaine St-Denis, France.
Christophe MartinaudCentre de Transfusion des Armées (CTSA), 92140 Clamart, France.
Josiane PillonelSanté Publique France, 94410 Saint Mau, France.
Martin TriboutEtablissement Français du Sang Occitanie (EFS Occitanie), 31059 Toulouse, France.
Claude MaugardEtablissement Français du Sang Occitanie (EFS Occitanie), 31059 Toulouse, France.
Josiane RelaveEtablissement Français du Sang Occitanie (EFS Occitanie), 31059 Toulouse, France.
Pascale RichardEtablissement Français du Sang (EFS), 93210 La Plaine St-Denis, France.
Pascal MorelEtablissement Français du Sang (EFS), 93210 La Plaine St-Denis, France.
Syria LapercheNational Reference Centre for Transfusion Infectious Risks, Institut National de la Transfusion Sanguine (INTS), 75015 Paris, France.ORCID 0000-0002-6497-0108
Établissement Français du Sang · FRInstitut National de la Transfusion Sanguine · FRInserm · FRSanté Publique France · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis B virus (HBV) infection is the most frequent viral infection found in blood donors (BDs) in France. We analyzed the epidemiological and sero-molecular data on HBV infection gathered over the past two decades by the French haemovigilance surveillance network, blood screening laboratories, and the national reference center for transfusion infectious risks (NRC). Between 2000 and 2020, 6149 of the 58,160,984 donations (1.06/10,000) tested HBV positive, 98% of them from first-time blood donors (FTBDs). In addition, 2212 (0.0071%) of the 30,977,753 donations screened for HBV DNA tested DNA positive, of which 25 (1.1%) were positive only for this marker. HBV prevalence decreased by 2.8-fold and the residual risk for transfusion-transmitted HBV infection decreased 13-fold and was divided by 13. The major risk factor for HBV infection was the origin of donors (endemic country, 66.5%), followed by parenteral exposure (10.7%). In the whole HBV-positive BD population, genotype D was predominant (41.8%), followed by genotypes A (26.2%) and E (20.4%), reflecting the geographical origin of donors. The low and decreasing prevalence and incidence of HBV infection in French BDs, coupled with a screening strategy using three HBV markers (HBsAg, anti-HBc and DNA), ensures a high level of blood safety, further reinforced by the implementation of pathogen-reduction measures.

Indexed as

Hepatitis BHepatitis B virusBlood DonorsDNA, ViralHepatitis B AntibodiesHepatitis B Surface AntigensHumansDNA, ViralHepatitis B AntibodiesHepatitis B Surface Antigensacute HBV infectionblood donationsHBVNAToccult B infection

Identifiers

PMID36423116
PMCPMC9693332
OpenAlexW4309315291

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.