Evidence map›Paper›PMID 36423084›Full record

ArticleVeterinary sciences2022

The Kitty Microbiome Project: Defining the Healthy Fecal "Core Microbiome" in Pet Domestic Cats.

Holly H Ganz, Guillaume Jospin, Connie A Rojas, Alex L Martin, Katherine Dahlhausen, Dawn D Kingsbury, Carlton X Osborne, Zhandra Entrolezo, Syd Redner, Bryan Ramirez and 6 more

Abstract read
In one paragraph

Article in Veterinary sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Immunoglobulin A protease fromGut microbes · 2026
    Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Variations in the Gut Microbiota of Stray and Domestic Cats.Animals : an open access journal from MDPI · 2026
    Article
  7. Frontiers in veterinary science · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
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  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Holly H GanzAnimalBiome, 400 29th Street, Suite 101, Oakland, CA 94609, USA.
Guillaume JospinAnimalBiome, 400 29th Street, Suite 101, Oakland, CA 94609, USA.
Connie A RojasDepartment of Evolution and Ecology, University of California, Davis, CA 95616, USA.ORCID 0000-0002-6097-8970
Alex L MartinAnimalBiome, 400 29th Street, Suite 101, Oakland, CA 94609, USA.
Katherine DahlhausenAnimalBiome, 400 29th Street, Suite 101, Oakland, CA 94609, USA.
Dawn D KingsburyAnimalBiome, 400 29th Street, Suite 101, Oakland, CA 94609, USA.
Carlton X OsborneAnimalBiome, 400 29th Street, Suite 101, Oakland, CA 94609, USA.
Zhandra EntrolezoAnimalBiome, 400 29th Street, Suite 101, Oakland, CA 94609, USA.
Syd RednerAnimalBiome, 400 29th Street, Suite 101, Oakland, CA 94609, USA.
Bryan RamirezAnimalBiome, 400 29th Street, Suite 101, Oakland, CA 94609, USA.
Jonathan A EisenDepartment of Evolution and Ecology, University of California, Davis, CA 95616, USA.
Madeleine LeahyDepartment of Evolution and Ecology, University of California, Davis, CA 95616, USA.
Chase KeatonDepartment of Evolution and Ecology, University of California, Davis, CA 95616, USA.
Janine WongDepartment of Evolution and Ecology, University of California, Davis, CA 95616, USA.
Jennifer GardyBill & Melinda Gates Foundation, Seattle, WA 98109, USA.
Jessica K JarettAnimalBiome, 400 29th Street, Suite 101, Oakland, CA 94609, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here, we present a taxonomically defined fecal microbiome dataset for healthy domestic cats (Felis catus) fed a range of commercial diets. We used this healthy reference dataset to explore how age, diet, and living environment correlate with fecal microbiome composition. Thirty core bacterial genera were identified. Prevotella, Bacteroides, Collinsella, Blautia, and Megasphaera were the most abundant, and Bacteroides, Blautia, Lachnoclostridium, Sutterella, and Ruminococcus gnavus were the most prevalent. While community composition remained relatively stable across different age classes, the number of core taxa present decreased significantly with age. Fecal microbiome composition varied with host diet type. Cats fed kibble had a slightly, but significantly greater number of core taxa compared to cats not fed any kibble. The core microbiomes of cats fed some raw food contained taxa not as highly prevalent or abundant as cats fed diets that included kibble. Living environment also had a large effect on fecal microbiome composition. Cats living in homes differed significantly from those in shelters and had a greater portion of their microbiomes represented by core taxa. Collectively our work reinforces the findings that age, diet, and living environment are important factors to consider when defining a core microbiome in a population.

Indexed as

agecore microbiomedietdomestic catsfecal microbiomeFIV infectiongut microbiomehealthy reference

Identifiers

PMID36423084
PMCPMC9698023

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.