Evidence map›Paper›PMID 36423067›Full record

ArticleVaccines2022

A Case of Purpura Annularis Telangiectodes of Majocchi after Anti-SARS-CoV-2 Pfizer-BioNTech Vaccine: Is There an Association?

Francesca Ambrogio, Carmelo Laface, Giorgia Sbarra, Raffaele Filotico, Girolamo Ranieri, Chiara Barlusconi, Aurora De Marco, Gerardo Cazzato, Domenico Bonamonte, Paolo Romita and 1 more

Abstract readCase Reports
In one paragraph

Article in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Francesca AmbrogioSection of Dermatology, Department of Biomedical Science and Human Oncology (DIMO), University of Bari "Aldo Moro", 70124 Bari, Italy.
Carmelo LafaceInterventional and Medical Oncology Unit, IRCCS Istituto Tumori "Giovanni Paolo II", 70124 Bari, Italy.ORCID 0000-0002-5074-4951
Giorgia SbarraSection of Dermatology, Department of Biomedical Science and Human Oncology (DIMO), University of Bari "Aldo Moro", 70124 Bari, Italy.
Raffaele FiloticoSection of Dermatology, Department of Biomedical Science and Human Oncology (DIMO), University of Bari "Aldo Moro", 70124 Bari, Italy.
Girolamo RanieriInterventional and Medical Oncology Unit, IRCCS Istituto Tumori "Giovanni Paolo II", 70124 Bari, Italy.
Chiara BarlusconiSection of Dermatology, Department of Biomedical Science and Human Oncology (DIMO), University of Bari "Aldo Moro", 70124 Bari, Italy.
Aurora De MarcoSection of Dermatology, Department of Biomedical Science and Human Oncology (DIMO), University of Bari "Aldo Moro", 70124 Bari, Italy.
Gerardo CazzatoSection of Pathology, Department of Emergency and Organ Transplantation (DETO), University of Bari "Aldo Moro", 70124 Bari, Italy.ORCID 0000-0003-0325-4316
Domenico BonamonteSection of Dermatology, Department of Biomedical Science and Human Oncology (DIMO), University of Bari "Aldo Moro", 70124 Bari, Italy.ORCID 0000-0002-1319-4946
Paolo RomitaSection of Dermatology, Department of Biomedical Science and Human Oncology (DIMO), University of Bari "Aldo Moro", 70124 Bari, Italy.
Caterina FotiSection of Dermatology, Department of Biomedical Science and Human Oncology (DIMO), University of Bari "Aldo Moro", 70124 Bari, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The advent of vaccines has drastically reduced the incidence, morbidity, and mortality related to COVID-19, and with the increase in the number of vaccinated subjects, there have been reports of some adverse events, including skin reactions. In this paper, we report a clinical case of Purpura Annularis Telangiectodes of Majocchi following a third-dose administration of the Pfizer-BioNTech COVID-19 vaccine. Almost 30 days after the third dose, the patient presented erythematous annular patches on the lower limbs with purpuric peripheral areas and a central clearing with no other symptoms. A dermoscopic examination showed capillaritis, reddish-brown dot-clods on a coppery-red background caused by leaky capillaries. To date, the causes of Majocchi's disease are not well-defined; in the literature, three vaccination-related cases have been reported: one after a flu vaccination and two after an anti-SARS-CoV-2 one. Dermatologists should be trained to promptly recognize these clinical manifestations after vaccination, which will likely become a common finding in daily clinical practice, especially given the large diffusion of SARS-CoV-2 vaccinations.

Indexed as

anti-SARS-CoV-2 vaccineMajocchi’s diseasemRNA vaccinepigmented purpuric dermatoses

Identifiers

PMID36423067
PMCPMC9697082

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.