Evidence map›Paper›PMID 36423056›Full record

ArticleVaccines2022

Plant-Produced S1 Subunit Protein of SARS-CoV-2 Elicits Immunogenic Responses in Mice.

Chalisa Panapitakkul, Narach Khorattanakulchai, Kaewta Rattanapisit, Theerakarn Srisangsung, Balamurugan Shanmugaraj, Supranee Buranapraditkun, Chutitorn Ketloy, Eakachai Prompetchara, Waranyoo Phoolcharoen

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Chalisa PanapitakkulCenter of Excellence in Plant-Produced Pharmaceuticals, Chulalongkorn University, Bangkok 10330, Thailand.
Narach KhorattanakulchaiCenter of Excellence in Plant-Produced Pharmaceuticals, Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0000-0002-3191-2585
Kaewta RattanapisitBaiya Phytopharm Co., Ltd., Bangkok 10330, Thailand.
Theerakarn SrisangsungBaiya Phytopharm Co., Ltd., Bangkok 10330, Thailand.
Balamurugan ShanmugarajBaiya Phytopharm Co., Ltd., Bangkok 10330, Thailand.
Supranee BuranapraditkunCenter of Excellence in Vaccine Research and Development (Chula VRC), Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0000-0001-9971-4318
Chutitorn KetloyCenter of Excellence in Vaccine Research and Development (Chula VRC), Chulalongkorn University, Bangkok 10330, Thailand.
Eakachai PrompetcharaCenter of Excellence in Vaccine Research and Development (Chula VRC), Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0000-0001-7565-9211
Waranyoo PhoolcharoenCenter of Excellence in Plant-Produced Pharmaceuticals, Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0000-0001-5958-7406
Chulalongkorn University · THThai Red Cross Society · TH

Funding

Baiya Phytopharm Co., Ltd. N/A
6 · The paper itself

Abstract

SARS-CoV-2 is responsible for the ongoing COVID-19 pandemic. The virus spreads rapidly with a high transmission rate among humans, and hence virus management has been challenging owing to finding specific therapies or vaccinations. Hence, an effective, low-cost vaccine is urgently required. In this study, the immunogenicity of the plant-produced S1 subunit protein of SARS-CoV-2 was examined in order to assess it as a potential candidate for SARS-CoV-2. The SARS-CoV-2 S1-Fc fusion protein was transiently produced in

Indexed as

plant-produced recombinant proteinSARS-CoV-2spike proteinsubunit vaccine

Identifiers

PMID36423056
PMCPMC9695278
OpenAlexW4309737095

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.