Evidence map›Paper›PMID 36422975›Full record

ReviewToxins2022

Superantigens, a Paradox of the Immune Response.

Sofia Noli Truant, Daniela María Redolfi, María Belén Sarratea, Emilio Luis Malchiodi, Marisa Mariel Fernández

Abstract readReview
In one paragraph

Review in Toxins, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Superantigens in Cancer Immunotherapy: Mechanisms, Engineering Strategies, and Therapeutic Potential.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Review
  2. Article
  3. The Pathogenicity Mechanisms ofInternational journal of molecular sciences · 2025
    Review
  4. Article
  5. A Comprehensive Review of the Bovine Immune Response to Pathogens.International journal of molecular sciences · 2025
    Review
  6. Journal of bacteriology · 2025
    Review
  7. Review
  8. Review
  9. Article
  10. Bacterial and host interactions inFrontiers in microbiology · 2025
    Review
  11. Article
  12. Review
  13. Review
  14. Toxic Shock Syndrome: A Literature Review.Antibiotics (Basel, Switzerland) · 2024
    Review
  15. Review
  16. Review
  17. Molecular Characteristics and Pathogenicity ofInternational journal of molecular sciences · 2023
    Review
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sofia Noli TruantCátedra de Inmunología-IDEHU (UBA-CONICET), Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín 956 4 Piso, Ciudad Autónoma de Buenos Aires 1113, Argentina.
Daniela María RedolfiCátedra de Inmunología-IDEHU (UBA-CONICET), Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín 956 4 Piso, Ciudad Autónoma de Buenos Aires 1113, Argentina.
María Belén SarrateaCátedra de Inmunología-IDEHU (UBA-CONICET), Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín 956 4 Piso, Ciudad Autónoma de Buenos Aires 1113, Argentina.ORCID 0000-0002-2144-7835
Emilio Luis MalchiodiCátedra de Inmunología-IDEHU (UBA-CONICET), Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín 956 4 Piso, Ciudad Autónoma de Buenos Aires 1113, Argentina.ORCID 0000-0001-7501-3330
Marisa Mariel FernándezCátedra de Inmunología-IDEHU (UBA-CONICET), Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín 956 4 Piso, Ciudad Autónoma de Buenos Aires 1113, Argentina.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Staphylococcal enterotoxins are a wide family of bacterial exotoxins with the capacity to activate as much as 20% of the host T cells, which is why they were called superantigens. Superantigens (SAgs) can cause multiple diseases in humans and cattle, ranging from mild to life-threatening infections. Almost all

Indexed as

Staphylococcus aureusSuperantigensAnimalsCattleEnterotoxinsExotoxinsHumansImmunityStaphylococcusEnterotoxinsExotoxinsSuperantigensenterotoxinimmunomodulationmolecular and cellular targetsstaphylococcal superantigentoxin pathogenicity

Identifiers

PMID36422975
PMCPMC9692936

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.