Evidence map›Paper›PMID 36422580›Full record

ArticlePathogens (Basel, Switzerland)2022

Quantitative G6PD Deficiency Screening in Routine Malaria Diagnostic Units in the Brazilian Amazon (SAFEPRIM): An Operational Mixed-Methods Study.

Jose Diego Brito-Sousa, Felipe Murta, Sheila Vitor-Silva, Vanderson Sampaio, Maxwell Mendes, Brenda Souza, Talita Batista, Alicia Santos, Leonardo Marques, Laila Barbosa and 15 more

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
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  7. Observational
  8. Review
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  12. Observational
  13. Pathogens (Basel, Switzerland) · 2023
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 5 institutions in 2 countries.

Jose Diego Brito-SousaFundação de Medicina Tropical Dr Heitor Vieira Dourado, Instituto de Pesquisa Clínica Carlos Borborema, Manaus 69040-000, Brazil.
Felipe MurtaFundação de Medicina Tropical Dr Heitor Vieira Dourado, Instituto de Pesquisa Clínica Carlos Borborema, Manaus 69040-000, Brazil.ORCID 0000-0003-4414-3989
Sheila Vitor-SilvaFundação de Medicina Tropical Dr Heitor Vieira Dourado, Instituto de Pesquisa Clínica Carlos Borborema, Manaus 69040-000, Brazil.
Vanderson SampaioFundação de Medicina Tropical Dr Heitor Vieira Dourado, Instituto de Pesquisa Clínica Carlos Borborema, Manaus 69040-000, Brazil.ORCID 0000-0001-7307-8851
Maxwell MendesFundação de Medicina Tropical Dr Heitor Vieira Dourado, Instituto de Pesquisa Clínica Carlos Borborema, Manaus 69040-000, Brazil.
Brenda SouzaFundação de Medicina Tropical Dr Heitor Vieira Dourado, Instituto de Pesquisa Clínica Carlos Borborema, Manaus 69040-000, Brazil.
Talita BatistaFundação de Medicina Tropical Dr Heitor Vieira Dourado, Instituto de Pesquisa Clínica Carlos Borborema, Manaus 69040-000, Brazil.
Alicia SantosFundação de Medicina Tropical Dr Heitor Vieira Dourado, Instituto de Pesquisa Clínica Carlos Borborema, Manaus 69040-000, Brazil.ORCID 0000-0002-5613-0467
Leonardo MarquesFundação de Medicina Tropical Dr Heitor Vieira Dourado, Instituto de Pesquisa Clínica Carlos Borborema, Manaus 69040-000, Brazil.ORCID 0000-0002-6739-2315
Laila BarbosaFundação de Medicina Tropical Dr Heitor Vieira Dourado, Instituto de Pesquisa Clínica Carlos Borborema, Manaus 69040-000, Brazil.ORCID 0000-0001-8480-0352
Patricia BalieiroFundação de Medicina Tropical Dr Heitor Vieira Dourado, Instituto de Pesquisa Clínica Carlos Borborema, Manaus 69040-000, Brazil.
Alexandre Silva-NetoFundação de Medicina Tropical Dr Heitor Vieira Dourado, Instituto de Pesquisa Clínica Carlos Borborema, Manaus 69040-000, Brazil.
Renata RabelloFundação de Medicina Tropical Dr Heitor Vieira Dourado, Instituto de Pesquisa Clínica Carlos Borborema, Manaus 69040-000, Brazil.
Marcelo BritoFundação de Medicina Tropical Dr Heitor Vieira Dourado, Instituto de Pesquisa Clínica Carlos Borborema, Manaus 69040-000, Brazil.
Emanuelle SilvaFundação de Medicina Tropical Dr Heitor Vieira Dourado, Instituto de Pesquisa Clínica Carlos Borborema, Manaus 69040-000, Brazil.
Sheila RodovalhoEscola Superior de Ciências da Saúde, Universidade do Estado do Amazonas, Manaus 69065-001, Brazil.ORCID 0000-0002-0019-9369
Ana Ruth ArcanjoLaboratório Central de Saúde Pública do Amazonas-LACEN/AM, Manaus 69020-040, Brazil.
Gisely MeloFundação de Medicina Tropical Dr Heitor Vieira Dourado, Instituto de Pesquisa Clínica Carlos Borborema, Manaus 69040-000, Brazil.
Judith RechtIndependent Consultant, North Bethesda, MD 20852, USA.ORCID 0000-0003-3572-0457
Gonzalo J DomingoDiagnostics Program, PATH, Seattle, WA 98121, USA.ORCID 0000-0002-1004-4395
Suiane ValleHospital Regional do Juruá, Cruzeiro do Sul 69895-000, Brazil.
Rodrigo SouzaCampus Floresta, Universidade Federal do Acre, Cruzeiro do Sul 69895-000, Brazil.ORCID 0000-0002-7775-6901
Theresa NakagawaFundação Oswaldo Cruz, Brasilia 70904-130, Brazil.
Wuelton MonteiroFundação de Medicina Tropical Dr Heitor Vieira Dourado, Instituto de Pesquisa Clínica Carlos Borborema, Manaus 69040-000, Brazil.ORCID 0000-0002-0848-1940
Marcus LacerdaFundação de Medicina Tropical Dr Heitor Vieira Dourado, Instituto de Pesquisa Clínica Carlos Borborema, Manaus 69040-000, Brazil.ORCID 0000-0003-3374-9985
Fundação de Medicina Tropical · BRFundação Oswaldo Cruz · BRPan American Health Organization (Brasil) · BRProgram for Appropriate Technology in Health · USUniversidade Federal do Acre · BR

Funding

Bill & Melinda Gates Foundation OPP1183951Coordenação de Aperfeicoamento de Pessoal de Nível Superior Finance code 001Fundação de Amparo à Pesquisa do Estado do Amazonas fellowshipFundação de Amparo à Pesquisa do Estado do Amazonas Pro-Estado grant 005/2019Oswaldo Cruz Foundation INOVA call nº 1702179682World Health Organization 001
6 · The paper itself

Abstract

backgroundGlucose-6-phosphate dehydrogenase (G6PD) deficiency testing is not routinely performed before primaquine treatment in most METHODS AND

findingsThis mixed-methods operational study was aimed at implementing the quantitative point-of-care Standard

interpretationPoint-of-care quantitative G6PD testing can be performed at MTUs in the Brazilian Amazon to inform treatment decisions with primaquine. Limitations related to technical and cultural aspects need to be addressed further when expanding screening to larger areas.

Indexed as

BrazileliminationG6PD deficiencyimplementationmalariaoperational studyPlasmodium vivaxprimaquinequantitative G6PD testSD biosensorStandard G6PD

Identifiers

PMID36422580
PMCPMC9696723
OpenAlexW4309008571

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.