Evidence map›Paper›PMID 36422579›Full record

ArticlePathogens (Basel, Switzerland)2022

Glycyrrhizin Interacts with TLR4 and TLR9 to Resolve

Mallika Somayajulu, Sharon A McClellan, Shukkur Muhammed Farooq, Ahalya Pitchaikannu, Shunbin Xu, Linda Hazlett

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mallika SomayajuluDepartment of Ophthalmology, Visual and Anatomical Sciences, Wayne State University School of Medicine, 540 E. Canfield, Detroit, MI 48201, USA.ORCID 0000-0002-5942-7135
Sharon A McClellanDepartment of Ophthalmology, Visual and Anatomical Sciences, Wayne State University School of Medicine, 540 E. Canfield, Detroit, MI 48201, USA.
Shukkur Muhammed FarooqDepartment of Ophthalmology, Visual and Anatomical Sciences, Wayne State University School of Medicine, 540 E. Canfield, Detroit, MI 48201, USA.
Ahalya PitchaikannuDepartment of Ophthalmology, Visual and Anatomical Sciences, Wayne State University School of Medicine, 540 E. Canfield, Detroit, MI 48201, USA.
Shunbin XuDepartment of Ophthalmology, Visual and Anatomical Sciences, Wayne State University School of Medicine, 540 E. Canfield, Detroit, MI 48201, USA.ORCID 0000-0002-6140-0943
Linda HazlettDepartment of Ophthalmology, Visual and Anatomical Sciences, Wayne State University School of Medicine, 540 E. Canfield, Detroit, MI 48201, USA.ORCID 0000-0003-1530-3242
Wayne State University · US

Funding

VISION RESEARCH--COREP30EY004068 · NEI · WAYNE STATE UNIVERSITY · PI LINDA D HAZLETT · 1985 to 2026
$13.2M
Role of Toll-Like Receptors in Bacterial KeratitisR01EY016058 · NEI · WAYNE STATE UNIVERSITY · PI HAZLETT, LINDA D · 2005 to 2023
$6.0M
The miR-183/96/182 Cluster in Pseudomonas aeruginosa-induced KeratitisR01EY026059 · NEI · WAYNE STATE UNIVERSITY · PI SHUNBIN XU · 2017 to 2026
$3.7M
NEI NIH HHS P30 EY004068NEI NIH HHS R01 EY016058NEI NIH HHS R01 EY026059
6 · The paper itself

Abstract

This study tests the mechanism(s) of glycyrrhizin (GLY) protection against

Indexed as

GLYkeratitisTLR4TLR9

Identifiers

PMID36422579
PMCPMC9694947
OpenAlexW4308972315

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.