Evidence map›Paper›PMID 36422291›Full record

ArticleMetabolites2022

A Time-Series Metabolomic Analysis of SARS-CoV-2 Infection in a Ferret Model.

Avinash V Karpe, Thao V Nguyen, Rohan M Shah, Gough G Au, Alexander J McAuley, Glenn A Marsh, Sarah Riddell, Seshadri S Vasan, David J Beale

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Avinash V KarpeLand and Water, Commonwealth Scientific and Industrial Research Organisation, Ecosciences Precinct, Dutton Park, QLD 4102, Australia.ORCID 0000-0002-3731-9598
Thao V NguyenLand and Water, Commonwealth Scientific and Industrial Research Organisation, Ecosciences Precinct, Dutton Park, QLD 4102, Australia.ORCID 0000-0003-3776-5392
Rohan M ShahLand and Water, Commonwealth Scientific and Industrial Research Organisation, Ecosciences Precinct, Dutton Park, QLD 4102, Australia.ORCID 0000-0003-4796-0394
Gough G AuCommonwealth Scientific and Industrial Research Organisation, Australian Centre for Disease Preparedness, Geelong, VIC 3220, Australia.
Alexander J McAuleyCommonwealth Scientific and Industrial Research Organisation, Australian Centre for Disease Preparedness, Geelong, VIC 3220, Australia.ORCID 0000-0002-7632-9633
Glenn A MarshCommonwealth Scientific and Industrial Research Organisation, Australian Centre for Disease Preparedness, Geelong, VIC 3220, Australia.ORCID 0000-0002-3469-1837
Sarah RiddellCommonwealth Scientific and Industrial Research Organisation, Australian Centre for Disease Preparedness, Geelong, VIC 3220, Australia.
Seshadri S VasanCommonwealth Scientific and Industrial Research Organisation, Australian Centre for Disease Preparedness, Geelong, VIC 3220, Australia.ORCID 0000-0002-7326-3210
David J BealeLand and Water, Commonwealth Scientific and Industrial Research Organisation, Ecosciences Precinct, Dutton Park, QLD 4102, Australia.ORCID 0000-0002-9948-9197
Commonwealth Scientific and Industrial Research Organisation · AU

Funding

Australian Centre for Disease Preparedness in providing their National Collaborative Research Infrastructure Strategy (NCRIS)Coalition for Epidemic Preparedness Innovations (CEPI)CSIRO's Future Science PlatformsUS FDA's Medical Countermeasures initiative 75F40121C00144
6 · The paper itself

Abstract

The global threat of COVID-19 has led to an increased use of metabolomics to study SARS-CoV-2 infections in animals and humans. In spite of these efforts, however, understanding the metabolome of SARS-CoV-2 during an infection remains difficult and incomplete. In this study, metabolic responses to a SAS-CoV-2 challenge experiment were studied in nasal washes collected from an asymptomatic ferret model (

Indexed as

animal modelsCOVID19ferrethost metabolic responsesmetabolomicsomicsSARS-CoV-2

Identifiers

PMID36422291
PMCPMC9699618
OpenAlexW4309705328

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.