Evidence map›Paper›PMID 36422282›Full record

ArticleMetabolites2022

Integration of Liver Glycogen and Triglyceride NMR Isotopomer Analyses Provides a Comprehensive Coverage of Hepatic Glucose and Fructose Metabolism.

Ivan Viegas, Giada Di Nunzio, Getachew D Belew, Alejandra N Torres, João G Silva, Luis Perpétuo, Cristina Barosa, Ludgero C Tavares, John G Jones

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Carbohydrate handling in frugivorous tambaqui (Colossoma macropomum): enzymatic and glycemic responses to dietary sugars.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Ivan ViegasCentre for Functional Ecology, Department of Life Sciences, University of Coimbra, Coimbra, Portugal.ORCID 0000-0003-2589-2212
Giada Di NunzioCenter for Neurosciences and Cell Biology, University of Coimbra, UC-Biotech, Biocant Park, Nucleo 8, Lote 4, 3060-197 Cantanhede, Portugal.ORCID 0000-0003-2423-498X
Getachew D BelewCenter for Neurosciences and Cell Biology, University of Coimbra, UC-Biotech, Biocant Park, Nucleo 8, Lote 4, 3060-197 Cantanhede, Portugal.ORCID 0000-0002-7338-1938
Alejandra N TorresCenter for Neurosciences and Cell Biology, University of Coimbra, UC-Biotech, Biocant Park, Nucleo 8, Lote 4, 3060-197 Cantanhede, Portugal.
João G SilvaCenter for Neurosciences and Cell Biology, University of Coimbra, UC-Biotech, Biocant Park, Nucleo 8, Lote 4, 3060-197 Cantanhede, Portugal.ORCID 0000-0002-1150-1893
Luis PerpétuoCenter for Neurosciences and Cell Biology, University of Coimbra, UC-Biotech, Biocant Park, Nucleo 8, Lote 4, 3060-197 Cantanhede, Portugal.
Cristina BarosaCenter for Neurosciences and Cell Biology, University of Coimbra, UC-Biotech, Biocant Park, Nucleo 8, Lote 4, 3060-197 Cantanhede, Portugal.
Ludgero C TavaresCIVG-Vasco da Gama Research Center, University School Vasco da Gama-EUVG, 3020-210 Coimbra, Portugal.ORCID 0000-0002-2324-1259
John G JonesCenter for Neurosciences and Cell Biology, University of Coimbra, UC-Biotech, Biocant Park, Nucleo 8, Lote 4, 3060-197 Cantanhede, Portugal.ORCID 0000-0002-3745-3885
Biocant · PTEscola Universitária Vasco da Gama · PTUniversity of Coimbra · PT

Funding

Fundação para a Ciência e Tecnologia FCT-FEDER-02/SAICT/2017/028147
6 · The paper itself

Abstract

Dietary glucose and fructose are both efficiently assimilated by the liver but a comprehensive measurement of this process starting from their conversion to sugar phosphates, involvement of the pentose phosphate pathway (PPP), and conversion to glycogen and lipid storage products, remains incomplete. Mice were fed a chow diet supplemented with 35 g/100 mL drinking water of a 55/45 fructose/glucose mixture for 18 weeks. On the final night, the sugar mixture was enriched with either [U-

Indexed as

13C NMRacetyl-CoAlipogenesispentose phosphate pathwaytriose phosphates

Identifiers

PMID36422282
PMCPMC9698123
OpenAlexW4309787648

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.