Evidence map›Paper›PMID 36422184›Full record

ArticleMedicina (Kaunas, Lithuania)2022

Endosonography-Guided Versus Percutaneous Gallbladder Drainage Versus Cholecystectomy in Fragile Patients with Acute Cholecystitis-A High-Volume Center Study.

Hayato Kurihara, Francesca M Bunino, Alessandro Fugazza, Enrico Marrano, Giulia Mauri, Martina Ceolin, Ezio Lanza, Matteo Colombo, Antonio Facciorusso, Alessandro Repici and 1 more

Open access · goldAbstract read
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Hayato KuriharaEmergency Surgery Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Francesca M BuninoEmergency Surgery and Trauma Section, Department of Surgery, IRCCS-Humanitas Research Hospital, 20089 Rozzano, Italy.ORCID 0000-0002-7600-9664
Alessandro FugazzaDivision of Gastroenterology and Digestive Endoscopy, Department of Gastroenterology, IRCCS-Humanitas Research Hospital, 20089 Rozzano, Italy.ORCID 0000-0003-0485-4903
Enrico MarranoGeneral Surgery, Hospital Universitari Parc Taulí, 08208 Sabadell, Spain.ORCID 0000-0001-6818-0448
Giulia MauriEmergency Surgery and Trauma Section, Department of Surgery, IRCCS-Humanitas Research Hospital, 20089 Rozzano, Italy.
Martina CeolinEmergency Surgery and Trauma Section, Department of Surgery, IRCCS-Humanitas Research Hospital, 20089 Rozzano, Italy.ORCID 0000-0002-4689-480X
Ezio LanzaDepartment of Diagnostic and Interventional Radiology, IRCCS-Humanitas Research Hospital, 20089 Rozzano, Italy.
Matteo ColomboDivision of Gastroenterology and Digestive Endoscopy, Department of Gastroenterology, IRCCS-Humanitas Research Hospital, 20089 Rozzano, Italy.ORCID 0000-0003-0715-8233
Antonio FacciorussoDepartment of Medical and Surgical Sciences, Gastroenterology Unit, University of Foggia, 71122 Foggia, Italy.
Alessandro RepiciDepartment of Biomedical Sciences, Humanitas University, 20090 Pieve Emanuele, Italy.
Andrea AnderloniGastroenterology and Digestive Endoscopy Unit, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.ORCID 0000-0002-1021-0031
IRCCS Humanitas Research Hospital · ITHumanitas University · ITDeleted InstitutionFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITPoliclinico San Matteo Fondazione · ITUniversity of Foggia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objectives: Acute cholecystitis is a frequent cause of admission to the emergency department, especially in old and frail patients. Percutaneous drainage (PT-GBD) and endosonographic guided drainage (EUS-GBD) could be an alternative option for relieving symptoms or act as a definitive treatment instead of a laparoscopic or open cholecystectomy (LC, OC). The aim of the present study was to compare different treatment groups. Materials and Methods: This is a five-year monocentric retrospective study including patients ≥65 years old who underwent an urgent operative procedure. A descriptive analysis was conducted comparing all treatment groups. A propensity score was estimated based on the ACS score, incorporated into a predictive model, and tested by recursive partitioning analysis. Results: 163 patients were included: 106 underwent a cholecystectomy (81 laparoscopic (LC) and 25 Open (OC)), 33 a PT-GBD and 21 EUS-GBD. The sample was categorized into three prognostic groups according to the adverse event occurrence rate. All patients treated with EUS-GBD or LC resulted in the low risk group, and the adverse event rate (AE) was 10/96 (10.4%). The AE was 4/28 (14.2%) and 21/36 (58.3%) in the middle- and high-risk groups respectively (p < 0.001). These groups included all the patients who underwent an OC or a PT-GBD. The PT-GBD group had a lower clinical success rate (55.5%) and higher RR (16,6%) when compared with other groups. Conclusions: Surgery still represents the gold standard for AC treatment. Nevertheless, EUS-GBD is a good alternative to PT-GBD in terms of clinical success, RR and AEs in all kinds of patients.

Indexed as

Cholecystitis, AcuteEndosonographyAgedCholecystectomyDrainageHumansRetrospective StudiesTreatment OutcomeACS scorecholecystectomycholecystitisendosonography-guided gallbladder drainagefrailtypercutaneous gallbladder drainage

Identifiers

PMID36422184
PMCPMC9699066
OpenAlexW4309787120

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.