Evidence map›Paper›PMID 36422106›Full record

ArticleJournal of personalized medicine2022

Workforce Considerations When Building a Precision Medicine Program.

Carrie L Blout Zawatsky, Jennifer R Leonhard, Megan Bell, Michelle M Moore, Natasha J Petry, Dylan M Platt, Robert C Green, Catherine Hajek, Kurt D Christensen

Abstract read
In one paragraph

Article in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Primary Care Providers' Experiences With an Active Elective Genetic Testing Program.Health education & behavior : the official publication of the Society for Public Health Education · 2025
    Article
  4. Article
  5. Article
  6. Attitudes, knowledge, and risk perceptions of patients who received elective genomic testing as a clinical service.Genetics in medicine : official journal of the American College of Medical Genetics · 2024
    Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Carrie L Blout ZawatskyGenomes2People, Department of Medicine (Genetics), Brigham and Women's Hospital, Boston, MA 02115, USA.ORCID 0000-0001-6328-0386
Jennifer R LeonhardDepartment of Genetics, Sanford Health, Bemidji, MN 56601, USA.ORCID 0000-0003-3803-2887
Megan BellDepartment of Genetics, Sanford Health, Sioux Falls, SD 57117, USA.
Michelle M MooreDepartment of Genetics, Sanford Health, Sioux Falls, SD 57117, USA.
Natasha J PetryDepartment of Sanford Imagenetics, Sanford Health, Sioux Falls, SD 57117, USA.ORCID 0000-0001-5089-9286
Dylan M PlattDepartment of Genetics, Sanford Health, Sioux Falls, SD 57117, USA.
Robert C GreenGenomes2People, Department of Medicine (Genetics), Brigham and Women's Hospital, Boston, MA 02115, USA.
Catherine HajekDepartment of Genetics, Sanford Health, Sioux Falls, SD 57117, USA.
Kurt D ChristensenBroad Institute, Cambridge, MA 02142, USA.ORCID 0000-0003-4068-776X

Funding

Return of Genomic Results and Estimating Penetrance in Population-Based CohortsR01HL143295 · NHLBI · BROAD INSTITUTE, INC. · PI CARSON, APRIL P, GREEN, ROBERT C. · 2019 to 2022
$7.2M
Cost-effectiveness of Whole Genome Sequencing of Healthy AdultsK01HG009173 · NHGRI · HARVARD PILGRIM HEALTH CARE, INC. · PI CHRISTENSEN, KURT DEREK · 2016 to 2020
$626k
NHGRI NIH HHS K01 HG009173NHLBI NIH HHS R01 HL143295
6 · The paper itself

Abstract

This paper describes one healthcare system's approach to strategically deploying genetic specialists and pharmacists to support the implementation of a precision medicine program. In 2013, Sanford Health initiated the development of a healthcare system-wide precision medicine program. Here, we report the necessary staffing including the genetic counselors, genetic counseling assistants, pharmacists, and geneticists. We examined the administrative and electronic medical records data to summarize genetic referrals over time as well as the uptake and results of an enterprise-wide genetic screening test. Between 2013 and 2020, the number of genetic specialists employed at Sanford Health increased by 190%, from 10.1 full-time equivalents (FTEs) to 29.3 FTEs. Over the same period, referrals from multiple provider types to genetic services increased by 423%, from 1438 referrals to 7517 referrals. Between 2018 and 2020, 11,771 patients received a genetic screening, with 4% identified with potential monogenic medically actionable predisposition (MAP) findings and 95% identified with at least one informative pharmacogenetic result. Of the MAP-positive patients, 85% had completed a session with a genetics provider. A strategic workforce staffing and deployment allowed Sanford Health to manage a new genetic screening program, which prompted a large increase in genetic referrals. This approach can be used as a template for other healthcare systems interested in the development of a precision medicine program.

Indexed as

delivery of health caregenetic counselinggenetic predisposition to dis-easegenetic testinghumansmass screeningpharmacogeneticsprecision medicineworkforce

Identifiers

PMID36422106
PMCPMC9692406

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.