ReviewJournal of personalized medicine2022
Multimorbidity, Frailty and Diabetes in Older People-Identifying Interrelationships and Outcomes.
Review in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The prevalence of disability in older adults with multimorbidity: a meta-analysis.Aging clinical and experimental research · 2024Pooled it
- Sodium-glucose cotransporter-2 inhibitors (SGLT2) in frail or older people with type 2 diabetes and heart failure: a systematic review and meta-analysis.Age and ageing · 2024Pooled it
- Prevalence of and Risk Factors for Drug-Related Readmissions in Older Adults: A Systematic Review and Meta-Analysis.Drugs & aging · 2024Pooled it
- Blood glucose and ketone testing practices in acute admissions of patients with diabetes mellitus: A retrospective audit.Irish journal of medical science · 2026Article
- Shifting barriers to exercise in later life: increasing impact among the oldest-old.Physical activity and nutrition · 2026Article
- Frailty and Sarcopenia in Elderly Diabetes Mellitus.Journal of clinical medicine · 2026Article
- Characteristics of above 65-year-olds with type 1 diabetes in the Finnish diabetic nephropathy study.Acta diabetologica · 2026Observational
- Personalized nutrition for healthy aging: precision diets based on genomic, metabolic, and microbiome profiles.Frontiers in nutrition · 2026Review
- Frailty in Critically Ill Cancer Patients in a Lower-middle Income Country-Prevalence, Risk Factors, and Impact on Acute Clinical Outcomes and Postdischarge Health-related Quality of Life: A Single Center Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026Article
- Individual and joint effects of overweight/obesity and the triglyceride-glucose index on mortality risk in type 2 diabetic patients: a retrospective cohort study in China.Frontiers in endocrinology · 2026Article
- Association Between Preoperative Frailty Using Frailty Index-Laboratory Test and Clinical Outcomes in Older Adults Undergoing Brain Tumor Surgery.Nursing & health sciences · 2025Article
- Associations of life's crucial 9 with mortality among older adults with frailty: a prospective cohort study from the NHANES 2007 to 2018.BMC geriatrics · 2025Article
- Associations between the risk of LUTS/BPH and the number and class of chronic diseases among middle-aged and elder men.Scientific reports · 2025Article
- Clinical outcomes of adverse drug reaction-related hospital admissions in older adults with diabetes.Frontiers in pharmacology · 2025Article
- The relationship between sleep disorders and frailty in stroke patients: the mediating role of self-efficacy.Frontiers in psychiatry · 2025Article
- Prevalence and predictors of frailty among community-dwelling older adults with hypertension in China.Revista da Associacao Medica Brasileira (1992) · 2025Article
- Digital interventions addressing the unmet needs of older adults with multimorbidity: a mixed-methods persona design approach.Frontiers in public health · 2025Article
- Metabolically "extremely unhealthy" obese and non-obese people with diabetes and the risk of cardiovascular adverse events: the Silesia Diabetes - Heart Project.Cardiovascular diabetology · 2024Observational
- Frailty and Cardiovascular Health.Journal of the American Heart Association · 2024Review
- Experiences of community-dwelling frail older adults with diabetes: Using phenomenological methods.Journal of Korean gerontological nursing · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Multimorbidity and frailty are highly prevalent in older people with diabetes. This high prevalence is likely due to a combination of ageing and diabetes-related complications and other diabetes-associated comorbidities. Both multimorbidity and frailty are associated with a wide range of adverse outcomes in older people with diabetes, which are proportionally related to the number of morbidities and to the severity of frailty. Although, the multimorbidity pattern or cluster of morbidities that have the most adverse effect are not yet well defined, it appears that mental health disorders enhance the multimorbidity-related adverse outcomes. Therefore, comprehensive diabetes guidelines that incorporate a holistic approach that includes screening and management of mental health disorders such as depression is required. The adverse outcomes predicted by multimorbidity and frailty appear to be similar and include an increased risk of health care utilisation, disability and mortality. The differential effect of one condition on outcomes, independent of the other, still needs future exploration. In addition, prospective clinical trials are required to investigate whether interventions to reduce multimorbidity and frailty both separately and in combination would improve clinical outcomes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.