Evidence map›Paper›PMID 36421994›Full record

Trial reportMarine drugs2022

Potentially Beneficial Effects on Healthy Aging by Supplementation of the EPA-Rich Microalgae

Lena Stiefvatter, Konstantin Frick, Katja Lehnert, Walter Vetter, Alexander Montoya-Arroyo, Jan Frank, Ulrike Schmid-Staiger, Stephan C Bischoff

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Marine drugs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Clarifying healthy aging: building a common language for policy innovation within the Age-It Research Program.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025
    Pooled it
  2. Trial
  3. Review
  4. Content of Vitamin DMetabolites · 2026
    Review
  5. Review
  6. Review
  7. Review
  8. ExploringMarine drugs · 2025
    Article
  9. Review
  10. Review
  11. The Ocean's Pharmacy: Health Discoveries in Marine Algae.Molecules (Basel, Switzerland) · 2024
    Review
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Lena StiefvatterInstitute of Clinical Nutrition, University of Hohenheim, Fruwirthstr. 12, 70593 Stuttgart, Germany.ORCID 0000-0002-6767-4101
Konstantin FrickFraunhofer Institute for Interfacial Engineering and Biotechnology, 70569 Stuttgart, Germany.
Katja LehnertInstitute of Food Chemistry, University of Hohenheim, 70593 Stuttgart, Germany.ORCID 0000-0003-4416-531X
Walter VetterInstitute of Food Chemistry, University of Hohenheim, 70593 Stuttgart, Germany.
Alexander Montoya-ArroyoDepartment of Food Biofunctionality, Institute of Nutritional Sciences, University of Hohenheim, 70593 Stuttgart, Germany.ORCID 0000-0003-1465-0322
Jan FrankDepartment of Food Biofunctionality, Institute of Nutritional Sciences, University of Hohenheim, 70593 Stuttgart, Germany.ORCID 0000-0002-7548-5829
Ulrike Schmid-StaigerFraunhofer Institute for Interfacial Engineering and Biotechnology, 70569 Stuttgart, Germany.ORCID 0000-0002-4961-6039
Stephan C BischoffInstitute of Clinical Nutrition, University of Hohenheim, Fruwirthstr. 12, 70593 Stuttgart, Germany.ORCID 0000-0003-2614-5948
University of Hohenheim · DEFraunhofer Institute for Interfacial Engineering and Biotechnology · DE

Funding

Gesellschaft für angewandte Vitaminforschung 111Society of Nutrition and Food Science 222
6 · The paper itself

Abstract

Dietary supplements that promote healthy aging are mostly warranted in an aging society. Because of age-related risks, anti-inflammatory and anti-oxidative agents such as microalgae are potential candidates for intervention. In a randomized controlled trial, we tested

Indexed as

DiatomsFatty Acids, Omega-3Healthy AgingMicroalgaeAgedDietary SupplementsEicosapentaenoic AcidFatty AcidsHumansPilot ProjectsEicosapentaenoic AcidFatty AcidsFatty Acids, Omega-3chrysolaminarineicosapentaenoic acidelderlyfucoxanthininflammageingomega-3-fatty acidsPhaeodactylum tricornutumβ-glucan

Identifiers

PMID36421994
PMCPMC9694444
OpenAlexW4309308605

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.