Evidence map›Paper›PMID 36421869›Full record

ArticleBrain sciences2022

Repetitive Anodal TDCS to the Frontal Cortex Increases the P300 during Working Memory Processing.

Angela Voegtle, Christoph Reichert, Hermann Hinrichs, Catherine M Sweeney-Reed

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. [A review of noninvasive brain-computer interfaces combined with transcranial electrical stimulation for neural rehabilitation].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Angela VoegtleNeurocybernetics and Rehabilitation, Department of Neurology, Otto von Guericke University, 39120 Magdeburg, Germany.ORCID 0000-0001-5715-2767
Christoph ReichertDepartment of Behavioral Neurology, Leibniz Institute for Neurobiology, 39118 Magdeburg, Germany.ORCID 0000-0002-8649-9791
Hermann HinrichsDepartment of Behavioral Neurology, Leibniz Institute for Neurobiology, 39118 Magdeburg, Germany.
Catherine M Sweeney-ReedNeurocybernetics and Rehabilitation, Department of Neurology, Otto von Guericke University, 39120 Magdeburg, Germany.ORCID 0000-0002-3684-1245
Center for Behavioral Brain Sciences · DEOtto-von-Guericke-Universität Magdeburg · DE

Funding

Deutsche Forschungsgemeinschaft SW214/2-1
6 · The paper itself

Abstract

Transcranial direct current stimulation (TDCS) is a technique with which neuronal activity, and therefore potentially behavior, is modulated by applying weak electrical currents to the scalp. Application of TDCS to enhance working memory (WM) has shown promising but also contradictory results, and little emphasis has been placed on repeated stimulation protocols, in which effects are expected to be increased. We aimed to characterize potential behavioral and electrophysiological changes induced by TDCS during WM training and evaluate whether repetitive anodal TDCS has a greater modulatory impact on the processes underpinning WM than single-session stimulation. We examined the effects of single-session and repetitive anodal TDCS to the dorsolateral prefrontal cortex (DLPFC), targeting the frontal-parietal network, during a WM task in 20 healthy participants. TDCS had no significant impact on behavioral measures, including reaction time and accuracy. Analyzing the electrophysiological response, the P300 amplitude significantly increased following repetitive anodal TDCS, however, positively correlating with task performance. P300 changes were identified over the parietal cortex, which is known to engage with the frontal cortex during WM processing. These findings support the hypothesis that repetitive anodal TDCS modulates electrophysiological processes underlying WM.

Indexed as

ERPn-backP300repetitiveTDCSworking memory

Identifiers

PMID36421869
PMCPMC9688092
OpenAlexW4310006961

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.