Evidence map›Paper›PMID 36421853›Full record

ArticleBrain sciences2022

MOGAD Involving Cranial Neuropathies: A Case Report and Review of Literature.

Yangsa Du, Ling Xiao, Zijin Ding, Kailing Huang, Bo Xiao, Li Feng

Open access · goldAbstract readCase Reports
In one paragraph

Article in Brain sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yangsa DuDepartment of Neurology, Xiangya Hospital, Central South University, Changsha 410008, China.ORCID 0000-0002-7446-5594
Ling XiaoDepartment of Neurology, Xiangya Hospital, Central South University, Changsha 410008, China.ORCID 0000-0001-9808-4000
Zijin DingDepartment of Anesthesiology, Xiangya Hospital, Central South University, Changsha 410008, China.
Kailing HuangDepartment of Neurology, Xiangya Hospital, Central South University, Changsha 410008, China.
Bo XiaoDepartment of Neurology, Xiangya Hospital, Central South University, Changsha 410008, China.
Li FengDepartment of Neurology, Xiangya Hospital, Central South University, Changsha 410008, China.ORCID 0000-0001-7658-1399
Central South University · CN

Funding

Hunan Provincial Natural Science Foundation of China 2021JJ31060Innovative construction foundation of Hunan province 2021SK4001National Natural Science Foundation of China 82071461
6 · The paper itself

Abstract

Myelin-oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD) is an autoimmune-mediated demyelinating disease of the central nervous system (CNS). Patients with MOGAD may develop any combination of optic neuritis (ON), myelitis, brainstem syndrome and encephalitis. Reports of MOGAD with cranial nerve involvement are rare. Herein, we report a MOGAD patient with cranial neuropathies. In addition, we summarized the clinical features of the previously reported six MOG-IgG-positive cases with cranial nerve involvement and discussed the underlying mechanisms of MOGAD involving cranial nerves. Cranial neuropathy is an emerging phenotype in MOGAD, which has characteristics of both central and peripheral nervous system (PNS) involvement, with the trigeminal nerve being the most commonly affected nerve. MOG antibody testing in patients with cranial neuropathies is warranted, and immunotherapy is advocated when the risk of relapse is high. Although higher antibody titers and persistently positive serological test results are predictive of disease recurrence, the long-term outcomes of MOG-IgG-positive patients with cranial neuropathies remain largely unknown.

Indexed as

anti-MOGcranial neuropathiesMOGADmyelin oligodendrocyte glycoproteinoptic neuritis

Identifiers

PMID36421853
PMCPMC9688642
OpenAlexW4308971909

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.