Evidence map›Paper›PMID 36421790›Full record

ArticleGenes2022

Congenital Heart Diseases: Genetic Risk Variants and Their Methylation Status.

Melissa Calzada-Dávila, Geovana Calvo-Anguiano, Laura E Martínez-de-Villarreal, José J Lugo-Trampe, Sandra M González-Peña, Patricia R Ancer-Rodríguez, María D Hernández-Almaguer, Luis D Campos-Acevedo

Open access · goldAbstract read
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Melissa Calzada-DávilaGenetics Department, Hospital Universitario "Dr. José Eleuterio González" and Medicine Faculty, Autonomous University of Nuevo León, Monterrey 64460, Mexico.ORCID 0000-0002-5236-2762
Geovana Calvo-AnguianoGenetics Department, Hospital Universitario "Dr. José Eleuterio González" and Medicine Faculty, Autonomous University of Nuevo León, Monterrey 64460, Mexico.
Laura E Martínez-de-VillarrealGenetics Department, Hospital Universitario "Dr. José Eleuterio González" and Medicine Faculty, Autonomous University of Nuevo León, Monterrey 64460, Mexico.ORCID 0000-0003-1442-9089
José J Lugo-TrampeGenetics Department, Hospital Universitario "Dr. José Eleuterio González" and Medicine Faculty, Autonomous University of Nuevo León, Monterrey 64460, Mexico.
Sandra M González-PeñaClinical Nutrition, Hospital Universitario "Dr. José Eleuterio González" and Medicine Faculty, Autonomous University of Nuevo León, Monterrey 64460, Mexico.ORCID 0000-0002-8935-8222
Patricia R Ancer-RodríguezClinical Nutrition, Hospital Universitario "Dr. José Eleuterio González" and Medicine Faculty, Autonomous University of Nuevo León, Monterrey 64460, Mexico.
María D Hernández-AlmaguerMedicine Faculty, Autonomous University of Baja California, Mexicali 21000, Mexico.
Luis D Campos-AcevedoGenetics Department, Hospital Universitario "Dr. José Eleuterio González" and Medicine Faculty, Autonomous University of Nuevo León, Monterrey 64460, Mexico.ORCID 0000-0003-3668-1613
Universidad Autónoma de Nuevo León · MXUniversidad Autónoma de Baja California · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: The interaction between single nucleotide variants (SNVs) associated with congenital heart diseases (CHDs) and their gene methylation status has not been well researched. The aim of the present study was to determine if there is a relationship between the methy lation status (MS) of genes and the allelic variants associated with CHDs. (2) Methods: Seven SNVs of the genes

Indexed as

Heart Defects, CongenitalAllelesCase-Control StudiesDNA MethylationHumansRisk Factorsatrial septal defectsAXIN1congenital heart diseaseepigeneticsfolic acid intakemethylation statusMTHFRTBX1TBX20ventricular septal defects

Identifiers

PMID36421790
PMCPMC9690480
OpenAlexW4309026044

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.