Evidence map›Paper›PMID 36421710›Full record

ArticleBiomolecules2022

Design, Synthesis, Kinetic Analysis and Pharmacophore-Directed Discovery of 3-Ethylaniline Hybrid Imino-Thiazolidinone as Potential Inhibitor of Carbonic Anhydrase II: An Emerging Biological Target for Treatment of Cancer.

Atteeque Ahmed, Mubashir Aziz, Syeda Abida Ejaz, Pervaiz Ali Channar, Aamer Saeed, Seema Zargar, Tanveer A Wani, Asad Hamad, Qamar Abbas, Hussain Raza and 1 more

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 4 countries.

Atteeque AhmedDepartment of Chemistry, Quaid-I-Azam University, Islamabad 45320, Pakistan.
Mubashir AzizDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan.
Syeda Abida EjazDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan.ORCID 0000-0002-8516-7234
Pervaiz Ali ChannarDepartment of Basic Sciences and Humanities, Faculty of Information Science and Humanities, Dawood University of Engineering and Technology, Karachi 74800, Pakistan.ORCID 0000-0002-0748-0129
Aamer SaeedDepartment of Chemistry, Quaid-I-Azam University, Islamabad 45320, Pakistan.
Seema ZargarDepartment of Biochemistry, College of Science, King Saud University, P.O. Box 22452, Riyadh 11451, Saudi Arabia.ORCID 0000-0002-5622-0841
Tanveer A WaniDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.ORCID 0000-0001-5623-2685
Asad HamadFaculty of Pharmacy, Grand Asian University Sialkot, Sialkot 51310, Pakistan.ORCID 0000-0003-4408-4683
Qamar AbbasDepartment of Biology, College of Science, University of Bahrain, Sakhir 32038, Bahrain.ORCID 0000-0003-4290-0798
Hussain RazaCollege of Natural Sciences, Department of Biological Sciences, Kongju National University, Gongju 32588, Republic of Korea.ORCID 0000-0002-3078-6660
Song Ja KimCollege of Natural Sciences, Department of Biological Sciences, Kongju National University, Gongju 32588, Republic of Korea.ORCID 0000-0001-6380-256X
Islamia University of Bahawalpur · PKKing Saud University · SAKongju National University · KRQuaid-i-Azam University · PKDawood University of Engineering and Technology · PKUniversity of Bahrain · BH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carbonic anhydrases (CA), having Zn

Indexed as

Carbonic Anhydrase IINeoplasmsAniline CompoundsCarbonic Anhydrase InhibitorsHumansKineticsMolecular Docking Simulation3-ethylanilineAniline CompoundsCarbonic Anhydrase IICarbonic Anhydrase Inhibitors3-ethylaniline hybrid imino-thiazolidinonescarbonic anhydrase IIDFT studiesdrug likeness scoresmolecular dockingmolecular dynamic simulation

Identifiers

PMID36421710
PMCPMC9687900
OpenAlexW4309608253

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.