Evidence map›Paper›PMID 36421695›Full record

ArticleBiomolecules2022

Structure/Function Studies on the Activation Motif of Two Non-Mammalian Mrap1 Orthologs, and Observations on the Phylogeny of Mrap1, Including a Novel Characterization of an Mrap1 from the Chondrostean Fish,

Robert M Dores, Greer McKinley, Audrey Meyers, Morgan Martin, Ciaran A Shaughnessy

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Robert M DoresDepartment of Biological Sciences, University of Denver, Denver, CO 80210, USA.ORCID 0000-0002-2640-8712
Greer McKinleyDepartment of Biological Sciences, University of Denver, Denver, CO 80210, USA.
Audrey MeyersDepartment of Biological Sciences, University of Denver, Denver, CO 80210, USA.
Morgan MartinDepartment of Biological Sciences, University of Denver, Denver, CO 80210, USA.ORCID 0000-0001-8216-4831
Ciaran A ShaughnessyDepartment of Biological Sciences, University of Denver, Denver, CO 80210, USA.ORCID 0000-0003-2146-9126
University of Denver · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In derived bony vertebrates, activation of the melanocortin-2 receptor (Mc2r) by its ACTH ligand requires chaperoning by the Mc2r accessory protein (Mrap1). The N-terminal domain of the non-mammalian tetrapod MRAP1 from chicken (c;

Indexed as

Adrenocorticotropic HormoneReceptor, Melanocortin, Type 2AlanineAnimalsCricetinaeCricetulusFishesPhylogenyAdrenocorticotropic HormoneAlanineReceptor, Melanocortin, Type 2evolutionMC2RMRAP1paddlefish

Identifiers

PMID36421695
PMCPMC9688151
OpenAlexW4308975473

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.