Evidence map›Paper›PMID 36421674›Full record

ReviewCurrent issues in molecular biology2022

Tumor Molecular and Microenvironment Characteristics in EBV-Associated Malignancies as Potential Therapeutic Targets: Focus on Gastric Cancer.

Aviva Atri-Schuller, Hassan Abushukair, Ludimila Cavalcante, Stijn Hentzen, Azhar Saeed, Anwaar Saeed

Abstract readReview
In one paragraph

Review in Current issues in molecular biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aviva Atri-SchullerDepartment of Internal Medicine, University of Cincinnati, Cincinnati, OH 45219, USA.
Hassan AbushukairFaculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan.ORCID 0000-0002-0068-5201
Ludimila CavalcanteDepartment of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, GA 30322, USA.ORCID 0000-0002-9676-0789
Stijn HentzenDepartment of Internal Medicine, Kansas University Medical Center, Kansas City, KS 66160, USA.ORCID 0000-0002-8177-6673
Azhar SaeedDepartment of Pathology, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA.
Anwaar SaeedDepartment of Medicine, Division of Medical Oncology, University of Kansas Cancer Center, 2330 Shawnee Mission Pkwy, Kansas City, KS 66205, USA.ORCID 0000-0001-8024-9401

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although most people are infected with Epstein-Barr Virus (EBV) during their lifetime, only a minority of them develop an EBV-associated malignancy. EBV acts in both direct and indirect ways to transform infected cells into tumor cells. There are multiple ways in which the EBV, host, and tumor environment interact to promote malignant transformation. This paper focuses on some of the mechanisms that EBV uses to transform the tumor microenvironment (TME) of EBV-associated gastric cancer (EBVaGC) for its benefit, including overexpression of Indoleamine 2,3-Dioxygenase 1 (IDO1), synergism between

Indexed as

EBVEBV-associated gastric cancer (EBVaGC)EBV malignanciesH. pyloriIDO1IFN-gammaM1M2TAMstumor microenvironment (TME)

Identifiers

PMID36421674
PMCPMC9689242

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.