Evidence map›Paper›PMID 36421612›Full record

ReviewHealthcare (Basel, Switzerland)2022

A Meta-Analysis of Group Cognitive Behavioral Therapy and Group Psychoeducation for Treating Symptoms and Preventing Relapse in People Living with Bipolar Disorder.

Marcus K Tan, Eik-Chao Chia, Wilson W Tam, Roger S McIntyre, Zhisong Zhang, Vu A Dam, Tham T Nguyen, Hoa T Do, Roger C Ho, Cyrus S H Ho

Abstract readReview
In one paragraph

Review in Healthcare (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Marcus K TanYong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.ORCID 0000-0002-3183-7116
Eik-Chao ChiaYong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.
Wilson W TamAlice Lee School of Nursing, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.ORCID 0000-0003-0641-3060
Roger S McIntyreBrain and Cognition Discovery Foundation, Toronto, ON M5S 1A1, Canada.
Zhisong ZhangFaculty of Education, Huaibei Normal University, Huaibei 235000, China.
Vu A DamInstitute for Global Health Innovations, Duy Tan University, Thanh Khê, Da Nang 550000, Vietnam.
Tham T NguyenInstitute for Global Health Innovations, Duy Tan University, Thanh Khê, Da Nang 550000, Vietnam.
Hoa T DoInstitute of Health Economics and Technology (iHEAT), Hanoi 100000, Vietnam.
Roger C HoInstitute for Health Innovation and Technology (iHealthtech), National University of Singapore, Singapore 119276, Singapore.ORCID 0000-0001-9629-4493
Cyrus S H HoDepartment of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.

Funding

2021 Humanities and Social Science research project of Anhui Universities SK2021ZD0047NUS Department of Psychological Medicine R-177-000-100-001/R-177-000-003-001/ R177000702733NUS iHeathtech Other Operating Expenses R-722-000-004-731Vingroup Innovation Foundation (VINIF) VINIF.2019.DA14
6 · The paper itself

Abstract

Objectives: This meta-analysis aims to evaluate the treatment outcomes of patients treated with Group cognitive behavioural therapy (GCBT) or group psychoeducation (GPE) as an adjunct to pharmacotherapy. Methods: Systematic search of PubMed, EMBASE, PsycINFO, and CENTRAL from inception till 1 March 2022 was conducted. Randomized-controlled-trials (RCTs) comparing GCBT/GPE with controls (treatment-as-usual/individualized therapy) in adults with bipolar disorder were eligible. The outcomes were relapse rates of any depressive or manic episodes and control of depressive and manic symptoms post-intervention. Overall odds-ratio was used to evaluate the relapse rates. Standard Mean Differences were pooled using a random-effects model for the control of depressive and manic symptoms. Results: 25 articles were assessed full-text independently by two members, and 11 studies were included in this meta-analysis. 601 and 590 participants were randomized into group-therapy (GCBT/GPE) and control, respectively. GPE significantly reduces relapse rates at post-intervention with Odds ratio of 0.43 (95% CI = 0.28-to-0.62, p < 0.0001) (I² = 41%) compared to control, however, no significant results were found for GPE on control of depressive or manic symptoms. No significant results were found for GCBT in all outcomes. Conclusion: This meta-analysis provides some evidence that GPE could be an efficacious treatment as an adjunct to treatment-as-usual in reducing the relapse rates of patients with bipolar disorder.

Indexed as

bipolar disorderchronic diseasecognitive behavioral therapydepressiongroupmaintenancemaniapsychoeducationpsychotherapyrecurrencerelapse

Identifiers

PMID36421612
PMCPMC9691241

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.