ArticleAntioxidants (Basel, Switzerland)2022
Conventional vs. Green Extraction Using Natural Deep Eutectic Solvents-Differences in the Composition of Soluble Unbound Phenolic Compounds and Antioxidant Activity.
Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Extraction of Phenolic Compounds from the Pulp ofACS omega · 2026Article
- NADES-Extracted SunGold Kiwifruit Polyphenols as Functional Ingredients in Antioxidant-Enriched Yoghurt.Antioxidants (Basel, Switzerland) · 2026Article
- Cosmeceutical Potential of Matcha (Molecules (Basel, Switzerland) · 2026Article
- A Review ofFoods (Basel, Switzerland) · 2026Review
- Sustainable Valorization of Avocado By-Products: Green Extraction of Phenolics with NaDES and Their Use in Fresh-Cut Fruit Preservation.Foods (Basel, Switzerland) · 2026Article
- Optimization of phenolics recovery from strychnos nux-vomica L. seed applying deep eutectic solvent-ultrasound assisted extraction.Scientific reports · 2026Article
- Chitosan Derivatives: Challenges and Opportunities in the Green and Sustainable Transition Era.Molecules (Basel, Switzerland) · 2026Review
- Fermentation of Common Nettle Extracts byFoods (Basel, Switzerland) · 2025Article
- Skin Performance of Innovative NaDES-Based Gels: In Vivo Evaluation of Anti-Irritation Potential and Short-Term Efficacy.Gels (Basel, Switzerland) · 2025Article
- Natural Deep Eutectic Solvent (NaDES) Extraction, HPLC-DAD Analysis, and Antioxidant Activity of ChileanAntioxidants (Basel, Switzerland) · 2025Article
- Article
- Preliminary Analysis of Bilberry NaDES Extracts as Versatile Active Ingredients of Natural Dermocosmetic Products: In Vitro Evaluation of Anti-Tyrosinase, Anti-Hyaluronidase, Anti-Collagenase, and UV Protective Properties.Plants (Basel, Switzerland) · 2025Article
- Microwave-assisted extraction of bioactive compounds from Urtica dioica using solvent-based process optimization and characterization.Scientific reports · 2025Article
- Valorization of Brewer's Spent Grain Through Ultrasound-Assisted Extraction of Phenolic Compounds Using Deep Eutectic Solvents.ACS omega · 2025Article
- Green Extraction of Antioxidant-Rich Flavonoids fromMolecules (Basel, Switzerland) · 2025Article
- Plant-Based Sunscreen Emulgel: UV Boosting Effect of Bilberry and Green Tea NaDES Extracts.Gels (Basel, Switzerland) · 2024Article
- An Eco-Friendly Supercritical COFoods (Basel, Switzerland) · 2024Article
Corrections and comments
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5 authors.
Funding
Abstract
The aim of this study was to investigate the effect of the use of green solvents, natural deep eutectic solvents (NaDES), in comparison with conventional solvents on the extraction of free unbound phenolic compounds and the antioxidant activity of extracts of dried bilberry fruit, bilberry leaves and green tea leaves. After preparation of the extracts via ultrasound-assisted extraction using NaDES and conventional solvents (water and ethanol), spectrophotometric determination of total phenolic and flavonoid content, HPLC analysis of extracted polyphenols and antioxidant determination using FRAP, DPPH and ABTS assays were conducted. The results showed that NaDES have a great potential as agents for the extraction of phenolic compounds with potent antioxidant activity; the highest values of phenolic content and antioxidant activity were detected in the samples obtained by extraction using the NaDES combination betaine + urea. The bilberry leaves exhibited the highest flavonoid content among all extracts and turned out to be more active than bilberry fruits, to which they are often just a by-product during processing. The most active extract of all was the betaine-urea green tea leaves extract. Further research into the most active NaDES extracts should be performed.
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