Evidence map›Paper›PMID 36421450›Full record

ArticleAntioxidants (Basel, Switzerland)2022

Inhibition of Tumor Growth and Modulation of Antioxidant Activity of Rhodoxanthin Isolated from

Daria-Antonia Dumitraş, Alexandra Iulia Dreanca, Emoke Pall, Adrian Florin Gal, Vasile Rus, Andreea Georgiana Morohoschi, Mihaela Cotul, Monica Irina Nan, Sanda Andrei

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2025
    Article
  2. Article
  3. Review
  4. Article
  5. In vivo (Athens, Greece)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Daria-Antonia DumitraşDepartment of Preclinical Sciences, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine, 400374 Cluj-Napoca, Romania.ORCID 0000-0001-8940-9651
Alexandra Iulia DreancaDepartment of Preclinical Sciences, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine, 400374 Cluj-Napoca, Romania.
Emoke PallDepartment of Clinical Sciences, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine, 400374 Cluj-Napoca, Romania.ORCID 0000-0002-7919-7381
Adrian Florin GalDepartment of Preclinical Sciences, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine, 400374 Cluj-Napoca, Romania.
Vasile RusDepartment of Preclinical Sciences, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine, 400374 Cluj-Napoca, Romania.ORCID 0000-0003-3706-887X
Andreea Georgiana MorohoschiDepartment of Preclinical Sciences, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine, 400374 Cluj-Napoca, Romania.
Mihaela CotulDepartment of Preclinical Sciences, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine, 400374 Cluj-Napoca, Romania.
Monica Irina NanDepartment of Preclinical Sciences, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine, 400374 Cluj-Napoca, Romania.
Sanda AndreiDepartment of Preclinical Sciences, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine, 400374 Cluj-Napoca, Romania.ORCID 0000-0003-0622-0963
University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca · RO

Funding

Romanian Ministry of Research, Innovation and Digitalization (PFE)-14 (ID 546)USAMV CN Romania 24905/08.11.2021
6 · The paper itself

Abstract

Malignant melanoma is the most aggressive type of skin cancer, and due to the numerous limitations of current treatment methods, there is an urgent need to develop novel approaches for both the prevention and treatment of malignant melanoma, with research-oriented bioactive substances representing a notable first step. The current study decided to expand on previous rhodoxanthin research by investigating the possible anti-tumor effect as well as the effect on the antioxidant status in the case of murine melanoma in an experimental model. The 21-day study was carried out on female C57BL/6J mice. On the first day of the experiment, they were subcutaneously inoculated with 10

Indexed as

antioxidant activityB16F10 murine melanomarhodoxanthinTaxus baccatatumor growth inhibition

Identifiers

PMID36421450
PMCPMC9687082
OpenAlexW4309708318

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.