Evidence map›Paper›PMID 36421423›Full record

ReviewAntioxidants (Basel, Switzerland)2022

Overview of the Mechanisms of Oxidative Stress: Impact in Inflammation of the Airway Diseases.

Giusy Daniela Albano, Rosalia Paola Gagliardo, Angela Marina Montalbano, Mirella Profita

Open access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 117 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
117citing papers in PubMed, 4 pooled it
29.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

117 citing papers in PubMed, 4 syntheses or guidelines pooled it, 214 citations in OpenAlex.

  1. Pooled it
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  3. Saffron (Frontiers in pharmacology · 2024
    Pooled it
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  9. Use of Antihistamine Drugs in Colitis: A Review.Pharmaceuticals (Basel, Switzerland) · 2026
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57 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Giusy Daniela AlbanoGiusy Daniela Albano, PhD Istituto di Farmacologia Traslazionale (IFT), Section of Palermo, Italy National Research Council of Italy (CNR), Via Ugo La Malfa 153, 90146 Palermo, Italy.
Rosalia Paola GagliardoGiusy Daniela Albano, PhD Istituto di Farmacologia Traslazionale (IFT), Section of Palermo, Italy National Research Council of Italy (CNR), Via Ugo La Malfa 153, 90146 Palermo, Italy.
Angela Marina MontalbanoGiusy Daniela Albano, PhD Istituto di Farmacologia Traslazionale (IFT), Section of Palermo, Italy National Research Council of Italy (CNR), Via Ugo La Malfa 153, 90146 Palermo, Italy.ORCID 0000-0001-5950-4834
Mirella ProfitaGiusy Daniela Albano, PhD Istituto di Farmacologia Traslazionale (IFT), Section of Palermo, Italy National Research Council of Italy (CNR), Via Ugo La Malfa 153, 90146 Palermo, Italy.
Istituto di Farmacologia Traslazionale · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation of the human lung is mediated in response to different stimuli (e.g., physical, radioactive, infective, pro-allergenic or toxic) such as cigarette smoke and environmental pollutants. They often promote an increase in inflammatory activities in the airways that manifest themselves as chronic diseases (e.g., allergic airway diseases, asthma, chronic bronchitis/chronic obstructive pulmonary disease (COPD) or even lung cancer). Increased levels of oxidative stress (OS) reduce the antioxidant defenses, affect the autophagy/mitophagy processes, and the regulatory mechanisms of cell survival, promoting inflammation in the lung. In fact, OS potentiate the inflammatory activities in the lung, favoring the progression of chronic airway diseases. OS increases the production of reactive oxygen species (ROS), including superoxide anions (O

Indexed as

asthmaCOPDlungnatural and synthetic antioxidantsoxidative stress

Identifiers

PMID36421423
PMCPMC9687037
OpenAlexW4309004601

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.