Evidence map›Paper›PMID 36421407›Full record

ArticleAntioxidants (Basel, Switzerland)2022

Investigation of the Possible Protective Effect of

Sevgi Gençosman, Deniz Ceylanlı, Ahmet Özer Şehirli, Kerem Teralı, Furkan Bölükbaşı, Şule Çetinel, Serkan Sayıner

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Sevgi GençosmanDepartment of Biochemistry, Faculty of Veterinary Medicine, Near East University, 99138 Nicosia, North Cyprus, Turkey.ORCID 0000-0003-1979-3058
Deniz CeylanlıDepartment of Biochemistry, Faculty of Veterinary Medicine, Near East University, 99138 Nicosia, North Cyprus, Turkey.ORCID 0000-0003-2352-052X
Ahmet Özer ŞehirliDepartment of Pharmacology, Faculty of Dentistry, Near East University, 99138 Nicosia, North Cyprus, Turkey.ORCID 0000-0002-5175-9290
Kerem TeralıDepartment of Medical Biochemistry, Faculty of Medicine, Cyprus International University, 99258 Nicosia, North Cyprus, Turkey.ORCID 0000-0002-9964-6383
Furkan BölükbaşıDepartment of Histology and Embryology, School of Medicine, Marmara University, 34722 İstanbul, Turkey.
Şule ÇetinelDepartment of Histology and Embryology, School of Medicine, Marmara University, 34722 İstanbul, Turkey.
Serkan SayınerDepartment of Biochemistry, Faculty of Veterinary Medicine, Near East University, 99138 Nicosia, North Cyprus, Turkey.ORCID 0000-0002-3297-5369
Near East University · CYMarmara University · TRCyprus International University · CY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Irinotecan (CPT-11) is a chemotherapeutic agent involved in the treatment regimens for several malignancies such as colorectal cancer.

Indexed as

cancer chemotherapyirinotecanmalondialdehydematrix metalloproteinaseN-acetylcysteineproinflammatory cytokines

Identifiers

PMID36421407
PMCPMC9686802
OpenAlexW4308877548

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.