Evidence map›Paper›PMID 36421387›Full record

ArticleBiology2022

The Role of Serotonergic Gene Methylation in Regulating Anxiety-Related Personality Traits in Chimpanzees.

Nicky Staes, Elaine E Guevara, William D Hopkins, Steven J Schapiro, Marcel Eens, Chet C Sherwood, Brenda J Bradley

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Nicky StaesCenter for the Advanced Study of Human Paleobiology, Department of Anthropology, The George Washington University, Washington, DC 20052, USA.ORCID 0000-0002-5444-4470
Elaine E GuevaraCenter for the Advanced Study of Human Paleobiology, Department of Anthropology, The George Washington University, Washington, DC 20052, USA.
William D HopkinsMichale E. Keeling Center for Comparative Medicine and Research, The University of Texas MD Anderson Cancer Center, Bastrop, TX 78602, USA.
Steven J SchapiroMichale E. Keeling Center for Comparative Medicine and Research, The University of Texas MD Anderson Cancer Center, Bastrop, TX 78602, USA.
Marcel EensBehavioural Ecology and Ecophysiology Group, Department of Biology, University of Antwerp, 2610 Antwerp, Belgium.ORCID 0000-0001-7538-3542
Chet C SherwoodCenter for the Advanced Study of Human Paleobiology, Department of Anthropology, The George Washington University, Washington, DC 20052, USA.
Brenda J BradleyCenter for the Advanced Study of Human Paleobiology, Department of Anthropology, The George Washington University, Washington, DC 20052, USA.
George Washington University · USThe University of Texas MD Anderson Cancer Center · USUniversity of Antwerp · BE

Funding

The National Center for Chimpanzee CareU42OD011197 · OD · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI ABEE, CHRISTIAN R · 2012 to 2019
$19.7M
National Science Foundation BCS-1733896National Science Foundation BSC-2127961National Science Foundation EF-2021785NIH HHS SMA-1542848NIH HHS U42 OD011197NIH HHS U42-OD011197Research Foundation Flanders 1124921Nthe James S. McDonnell Foundation 220020293
6 · The paper itself

Abstract

While low serotonergic activity is often associated with psychological disorders such as depression, anxiety, mood, and personality disorders, variations in serotonin also contribute to normal personality differences. In this study, we investigated the role of blood DNA methylation levels at individual CpG sites of two key serotonergic genes (serotonin receptor gene 1A,

Indexed as

behavioral styleIllumina Infinium Methylation EPIC arrayprimaterearing

Identifiers

PMID36421387
PMCPMC9687614
OpenAlexW4309284993

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.