Evidence map›Paper›PMID 36421353›Full record

ArticleCurrent oncology (Toronto, Ont.)2022

Expression of IRAK1 in Hepatocellular Carcinoma, Its Clinical Significance, and Docking Characteristics with Selected Natural Compounds.

Chaoying Song, Xinyu Gu, Ruifang Li

Open access · goldAbstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Chaoying SongDepartment of Pharmaceutical Sciences, School of Basic Medical Sciences, Henan University of Science and Technology, Luoyang 471023, China.
Xinyu GuDepartment of Pharmaceutical Sciences, School of Basic Medical Sciences, Henan University of Science and Technology, Luoyang 471023, China.
Ruifang LiDepartment of Pharmaceutical Sciences, School of Basic Medical Sciences, Henan University of Science and Technology, Luoyang 471023, China.
Henan University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to explore clinical significance of interleukin-1 receptor-associated kinase 1 (IRAK1) in the diagnosis, prognosis, and targeted therapy of hepatocellular carcinoma. A systematic analysis based on the cancer genome atlas (TCGA) indicated that IRAK1 was highly expressed in 18 cancer types (

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsBiomarkers, TumorHumansInterleukin-1 Receptor-Associated KinasesMolecular Docking SimulationBiomarkers, TumorInterleukin-1 Receptor-Associated KinasesIRAK1 protein, humanhepatocellular carcinomaIRAK1IRAK1/NF-κB signalingnatural compoundtargeted therapyTP53 mutation

Identifiers

PMID36421353
PMCPMC9689133
OpenAlexW4309457234

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.