Evidence map›Paper›PMID 36421312›Full record

ArticleAntibiotics (Basel, Switzerland)2022

Genome-Wide Analysis of Innate Susceptibility Mechanisms of

Muhammad Yasir, A Keith Turner, Sarah Bastkowski, Martin Lott, Emma R Holden, Andrea Telatin, Andrew J Page, Mark A Webber, Ian G Charles

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 63% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Muhammad YasirQuadram Institute Bioscience, Rosalind Franklin Road, Norwich NR4 7UQ, UK.ORCID 0000-0001-9437-2996
A Keith TurnerQuadram Institute Bioscience, Rosalind Franklin Road, Norwich NR4 7UQ, UK.ORCID 0000-0002-3680-6343
Sarah BastkowskiQuadram Institute Bioscience, Rosalind Franklin Road, Norwich NR4 7UQ, UK.
Martin LottQuadram Institute Bioscience, Rosalind Franklin Road, Norwich NR4 7UQ, UK.
Emma R HoldenQuadram Institute Bioscience, Rosalind Franklin Road, Norwich NR4 7UQ, UK.ORCID 0000-0002-0811-1675
Andrea TelatinQuadram Institute Bioscience, Rosalind Franklin Road, Norwich NR4 7UQ, UK.ORCID 0000-0001-7619-281X
Andrew J PageQuadram Institute Bioscience, Rosalind Franklin Road, Norwich NR4 7UQ, UK.
Mark A WebberQuadram Institute Bioscience, Rosalind Franklin Road, Norwich NR4 7UQ, UK.
Ian G CharlesQuadram Institute Bioscience, Rosalind Franklin Road, Norwich NR4 7UQ, UK.
Quadram Institute · GBNorwich Research Park · GB

Funding

Biotechnology and Biological Sciences Research Council BB/R012504/1 and BBS/E/F/000PR10349Medical Research Council MR/L015080/1Medical Research Council MR/T030062/1
6 · The paper itself

Abstract

Colistin is an antibiotic that has seen increasing clinical use for the treatment of human infections caused by Gram-negative pathogens, particularly due to the emergence of multidrug-resistant pathogens. Colistin resistance is also a growing problem and typically results from alterations to lipopolysaccharides mediated by phosphoethanolamine (pETn) transferase enzymes which can be encoded on the chromosome, or plasmids. In this study, we used 'TraDIS-Xpress' (

Indexed as

colistinEscherichia coliresistance mechanismsTraDIS-Xpress

Identifiers

PMID36421312
PMCPMC9687012
OpenAlexW4309787462

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.