ArticleAntibiotics (Basel, Switzerland)2022
Comparison of Patient-Reported Outcomes Measures and Quality-Adjusted Life Years Following One- and Two-Stage Septic Knee Exchange.
Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Functional and quality-of-life outcomes after metal-on-polyethylene articulating spacer implantation for periprosthetic knee infection: a retrospective evaluation of a prospectively collected cohort.Archives of orthopaedic and trauma surgery · 2026Observational
- Comparable reinfection rates between one-stage and two-stage revision total knee arthroplasty with gastrocnemius flap reconstruction for periprosthetic joint infection: A systematic review and meta-analysis.Journal of experimental orthopaedics · 2026Review
- Surgical revision in the presence of an S. aureus infection increases virulence factor expression and activates a multi-tissue inflammatory response.NPJ biofilms and microbiomes · 2025Article
- One- versus two-stage septic hip and knee revision surgery: a comparative cohort outcome study with short- to mid-term follow-up.Journal of bone and joint infection · 2025Article
- The top ten benefits of one-stage septic exchange in the management of periprosthetic joint infections.Archives of orthopaedic and trauma surgery · 2024Article
- A Meta-Analysis of Success Rates of One-Stage Versus Two-Stage Revisions in Knee Prosthetic Joint Infections.Cureus · 2024Review
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
(1) Background: Periprosthetic joint infection (PJI) can be managed with one- or two-stage revision surgery protocol. Despite several studies analyzing the eradication rates between both procedures, there are no comparative studies that analyze patient-reported outcome measures (PROMs) and quality-adjusted life years (QALYs) in both treatment strategies. (2) Methods: All patients who underwent a two-stage knee revision between January 2017 to December 2018, due to a periprosthetic joint infection were included in the study. From the time interval, we selected a comparative group with the one-stage septic procedure. All patients received the following questionnaires: Oxford Knee Score, EQ-5D-5L, SSQ-8, and the SF-36. Additionally, demographic patient data were collected. The quality-adjusted life years (QALY) were calculated using the EQ-5D-5L. (3) Results: A total of 35 patients with a mean age of 67.7 years (SD = 8.9) were included in the final evaluation. The mean follow-up period was 54.5 months (SD = 5.5). There was no statistically significant difference regarding the Charlson Comorbidity Index (CCI), postoperative complications, or all evaluated questionnaires. There was no statistically significant difference in QALYs between the one- and two-stage revision. (4) Conclusion: Our study results show that the one-stage revision for PJI achieves similar PROMs compared to two-stage revision.
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