Evidence map›Paper›PMID 36421216›Full record

ArticleChildren (Basel, Switzerland)2022

Impressive Nasal Septum Regeneration after Cord Blood Platelet Gel (CBPG) in Extreme Premature Neonate with Non-Invasive Ventilation: A Case Report.

Raffaele Falsaperla, Giulia Marialidia Biondi, Milena Motta, Pasquale Gallerano, Giusi Tancredi, Piero Pavone, Martino Ruggieri

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Children (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 84% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Cord Blood-Derived Platelet Gel in Wound Healing: From Biological Rationale to Clinical Application.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Raffaele FalsaperlaNeonatal Intensive Care Unit, AUO Policlinico "Rodolico-San Marco", University of Catania, 95121 Catania, Italy.ORCID 0000-0002-4482-3506
Giulia Marialidia BiondiPostgraduate Training Program in Pediatrics, Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.
Milena MottaNeonatal Intensive Care Unit, AUO Policlinico "Rodolico-San Marco", University of Catania, 95121 Catania, Italy.
Pasquale GalleranoTransfusional Medicine, Complex Operative Unit, PO "Giovanni Paolo II", 92019 Sciacca, Italy.
Giusi TancrediTransfusional Medicine, Complex Operative Unit, PO "Giovanni Paolo II", 92019 Sciacca, Italy.
Piero PavoneSection of Pediatrics and Child Neuropsichiatry, Department of Child and Experimental Medicine, University of Catania, AOU "Policlinico PO" G. Rodolico, 95123 Catania, Italy.ORCID 0000-0002-5600-9560
Martino RuggieriUnit of Rare Diseases of the Nervous System in Childhood, Department of Clinical and Experimental Medicine, Section of Pediatrics and Child Neuropsichiatry, University of Catania, AOU "Policlinico PO" G. Rodolico, 95123 Catania, Italy.
University of Catania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe evaluated the efficacy of Cord Blood Platelet Gel (CBPG) in the regenerative reconstruction of the nasal septal tissue of a preterm infant undergoing non-invasive ventilation.

methodsA CBPC treatment was used to enhance the regeneration of the nasal septum of a premature patient in an experimental way, evaluating the efficacy described in the literature (selective bibliographic search in PubMed) of the use of blood products for non-transfusion purposes.

resultsA partial but satisfactory regeneration of the patient's nasal septum was observed. Using the free NIH Image J online software, we were able to calculate the regenerated surface (about 83% of the destroyed cartilage).

conclusionsThe use of platelet gel has been a promising alternative to surgical treatment in patients with severe damage to the nasal septum.

Indexed as

nasal septumnon-invasive ventilationplatelet gelprematurityseptal tissue

Identifiers

PMID36421216
PMCPMC9689260
OpenAlexW4309287215

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.