ArticleBioengineering (Basel, Switzerland)2022
Heart and Breathing Rate Variations as Biomarkers for Anxiety Detection.
Article in Bioengineering (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 38 citations in OpenAlex.
- Detecting Distress in Cognitively Impaired People to Prevent Suffering: Protocol for an Observational Feasibility Study of a Radar-Based Technology Augmented with Photoplethysmographic Sensors and Audio Signals (SURREAL).Sensors (Basel, Switzerland) · 2026Article
- Wearable ECG and PPG for anxiety detection: a translational digital medicine perspective.NPJ digital medicine · 2026Article
- Dream content and slow waves benefit prey against predator in a video game confrontation.Scientific reports · 2026Article
- α2δ-1-NMDAR1 complex in the hypothalamic paraventricular nucleus mediates anxiety-induced sympathetic hyperactivity.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2026Article
- Baseline normalization choices inflate classification performance in wearable health monitoring: quantification and mitigation strategies.Frontiers in digital health · 2026Article
- It's About Time-Breathing Dynamics Modulate Emotion and Cognition.Psychophysiology · 2025Article
- The role of face regions in remote photoplethysmography for contactless heart rate monitoring.NPJ digital medicine · 2025Article
- A Co-Segmentation Algorithm to Predict Emotional Stress From Passively Sensed mHealth Data.Statistics in medicine · 2025Article
- Detecting sources of anger in automated driving: driving-related and external factor.Frontiers in neuroergonomics · 2025Article
- In-silico simultaneous respiratory and circulatory measurement during voluntary breathing, exercise, and mental stress: A computational approach.PLoS computational biology · 2024Article
- Recent Advances in Wearable Healthcare Devices: From Material to Application.Bioengineering (Basel, Switzerland) · 2024Review
- Sex differences in heart rate variability measures that predict alcohol drinking in rats.Addiction biology · 2024Article
- Multi-omics approaches in psychoneuroimmunology and health research: Conceptual considerations and methodological recommendations.Brain, behavior, and immunity · 2023Article
- The Potential of Heart Rate Variability Monitoring for Mental Health Assessment in Top Wheel Gymnastics Athletes: A Single Case Design.Applied psychophysiology and biofeedback · 2023Article
- Prediction of Impulsive Aggression Based on Video Images.Bioengineering (Basel, Switzerland) · 2023Article
- Assessment of a Person's Emotional State Based on His or Her Posture Parameters.Sensors (Basel, Switzerland) · 2023Article
- Heart rate variability measures indicating sex differences in autonomic regulation during anxiety-like behavior in rats.Frontiers in psychiatry · 2023Article
- [Parallel mediating effects of maladaptive cognitive emotion regulation strategies and impulsivity on the relationship between trait anxiety and nonZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciencesArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
With advances in portable and wearable devices, it should be possible to analyze and interpret the collected biosignals from those devices to tailor a psychological intervention to help patients. This study focuses on detecting anxiety by using a portable device that collects electrocardiogram (ECG) and respiration (RSP) signals. The feature extraction focused on heart-rate variability (HRV) and breathing-rate variability (BRV). We show that a significant change in these signals occurred between the non-anxiety-induced and anxiety-induced states. The HRV biomarkers were the mean heart rate (MHR; p¯ = 0.04), the standard deviation of the heart rate (SD; p¯ = 0.01), and the standard deviation of NN intervals (SDNN; p¯ = 0.03) for ECG signals, and the mean breath rate (MBR; p¯ = 0.002), the standard deviation of the breath rate (SD; p¯ < 0.0001), the root mean square of successive differences (RMSSD; p¯ < 0.0001) and SDNN (p¯ < 0.0001) for RSP signals. This work extends the existing literature on the relationship between stress and HRV/BRV by being the first to introduce a transitional phase. It contributes to systematically processing mental and emotional impulse data in humans measured via ECG and RSP signals. On the basis of these identified biomarkers, artificial-intelligence or machine-learning algorithms, and rule-based classification, the automated biosignal-based psychological assessment of patients could be within reach. This creates a broad basis for detecting and evaluating psychological abnormalities in individuals upon which future psychological treatment methods could be built using portable and wearable devices.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.