Evidence map›Paper›PMID 36421053›Full record

ArticleGlobal spine journal2024

High-Demand Spinal Deformity With Multi-Rod Constructs and Porous Fusion/Fixation Implants: A Finite Element Study.

Matteo Panico, Ruchi D Chande, Derek P Lindsey, Tomaso Maria Tobia Villa, Scott A Yerby, Marco Brayda-Bruno, Tito Bassani, David W Polly, Fabio Galbusera

Open access · goldAbstract read
In one paragraph

Article in Global spine journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. S2AI and iliac screw prominence and removal for symptomatic prominence: a systematic review.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Matteo PanicoIRCCS Istituto Ortopedico Galeazzi, Milan, Italy.ORCID 0000-0001-5520-2054
Ruchi D ChandeSI-BONE, Inc., Santa Clara, CA, USA.
Derek P LindseySI-BONE, Inc., Santa Clara, CA, USA.ORCID 0000-0003-2699-8190
Tomaso Maria Tobia VillaIRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
Scott A YerbySI-BONE, Inc., Santa Clara, CA, USA.
Marco Brayda-BrunoIRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
Tito BassaniIRCCS Istituto Ortopedico Galeazzi, Milan, Italy.ORCID 0000-0003-3312-1565
David W PollyDepartment of Orthopedic Surgery, University of Minnesota, Minnesota, MN, USA.
Fabio GalbuseraSpine Center, Schulthess Clinic, Zurich, Switzerland.
Istituto Ortopedico Galeazzi · ITSI-Bone (United States) · USSchulthess-Klinik · CHUniversity of Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designBasic science (finite element analysis).

objectivesPedicle subtraction osteotomy (PSO) at L5 is an effective treatment for sagittal imbalance, especially in select cases of patients showing kyphosis with the apex at L4-L5 but has been scarcely investigated. The aim of this study was to simulate various "high-demand" instrumentation approaches, including varying numbers of rods and sacropelvic implants, for the stabilization of a PSO at L5.

methodsA finite element model of T10-pelvis was modified to simulate posterior fixation with pedicle screws and rods from T10 to S1, alone or in combination with an L5 PSO. Five additional configurations were then created by employing rods and novel porous fusion/fixation implants across the sacroiliac joints, in varying numbers. All models were loaded using pure moments of 7.5 Nm in flexion-extension, lateral bending, and axial rotation.

resultsThe osteotomy resulted in a general increase in motion and stresses in posterior rods and S1 pedicle screws. When the number of rods was varied, three- and four-rod configurations were effective in limiting the maximal rod stresses; values approached those of posterior fixation with no osteotomy. Maximum stresses in the accessory rods were similar to or less than those observed in the primary rods. Multiple sacropelvic implants were effective in reducing range of motion, particularly of the SIJ.

conclusionsMulti-rod constructs and sacropelvic fixation generally reduced maximal implant stresses and motion in comparison with standard posterior fixation, suggesting a reduced risk of rod breakage and increased joint stability, respectively, when a high-demand construct is utilized for the correction of sagittal imbalance.

Indexed as

biomechanicsfinite elementhigh-demand constructL5multi-rodpedicle subtraction osteotomy

Identifiers

PMID36421053
PMCPMC11289527
OpenAlexW4309885535

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.