Observational studyCartilage2022
Impact of the Weightbearing Line on Cartilage Regeneration of the Medial Knee Compartment after Open-Wedge High Tibial Osteotomy, Based on Second-Look Arthroscopy.
Observational study in Cartilage, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The trial behind it
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Who cites it
11 citing papers in PubMed.
- Influences of Tibial Plateau Morphology on JLCA Change, Clinical Outcomes and Cartilage Regeneration After Medial Opening Wedge High Tibial Osteotomy.Orthopaedic journal of sports medicine · 2026Article
- Five-year outcomes of medial open-wedge high tibial osteotomy with lateral supplemental lag screw in patients with obesity.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2026Article
- Relationships Among Bone Marrow Lesions, Cartilage Improvement, and Short- to Midterm Patient-Reported Outcomes After Opening-Wedge High Tibial Osteotomy.Orthopaedic journal of sports medicine · 2026Article
- CPAK phenotypes in medial open wedge high tibial osteotomy: undercorrection as the key factor influencing clinical outcomes and cartilage regeneration.Journal of orthopaedic surgery and research · 2026Article
- High tibial osteotomy achieves unloading of the medial tibiofemoral compartment irrespective of arthritic status or medial collateral ligament release: A biomechanical assessment.Journal of experimental orthopaedics · 2026Article
- [Impact of lower limb weight bearing line ratio on motor function recovery after high tibial osteotomy].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025Article
- Alignment rod and gap measurement methods achieve comparable alignment correction in opening wedge high tibial osteotomy for varus osteoarthritic knees.Journal of experimental orthopaedics · 2024Article
- Preoperative Joint Line Convergence Angle as an Indicator of Clinical Outcomes and Accuracy of Alignment Correction After Double-Level Osteotomy.Orthopaedic journal of sports medicine · 2024Article
- Joint line convergence angle is the most associated alignment factor with the severity of medial knee osteoarthritis.Journal of experimental orthopaedics · 2024Article
- Effects of concurrent cartilage procedures on cartilage regeneration in high tibial osteotomy: a systematic review.Knee surgery & related research · 2024Review
- Change in Cartilage Status of Medial Compartment after Open-Wedge High Tibial Osteotomy without Cartilage Regeneration Procedure: Second Look Arthroscopic Assessment.Biomedicines · 2023Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveCartilage regeneration is multifactorial. This study aimed to optimize the biomechanical factor of weightbearing loading allowing for cartilage regeneration and elucidate the association between cartilage regeneration and clinical outcomes after medial open-wedge high tibial osteotomy (OWHTO).
designThis was a retrospective, observational study of 142 patients who underwent OWHTO and subsequently underwent second-look arthroscopic assessment at a single orthopedic surgery center in Japan. Clinical and radiographic outcomes were compared between patients with (group R) and without (group D) cartilage regeneration, measured using the International Cartilage Repair Society grading system and the macroscopic staging system at the time second-look arthroscopy was performed. A receiver operating characteristic curve analysis was used to determine the optimal weightbearing line ratio (WBLR) for cartilage regeneration.
resultsGroup R included 82 knees, and group D 60 knees. The WBLR was higher in group R (60.9% ± 6.7%) than in group D (55.6% ± 7.6%) (
conclusionsA WBLR of 62% was associated with cartilage regeneration after OWHTO and high patient-reported clinical outcomes.
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