Evidence map›Paper›PMID 36420912›Full record

ReviewToxicology and industrial health2023

Analysis of dermal exposure assessment in the US Environmental Protection Agency Toxic Substances Control Act risk evaluations of chemical manufacturing.

Heather N Lynch, Lauren E Gloekler, Laura H Allen, Joshua R Maskrey, Christopher Bevan, Andrew Maier

Open access · hybridAbstract readReview
In one paragraph

Review in Toxicology and industrial health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Heather N Lynch205740Stantec (ChemRisk), Boston, MA, USA.ORCID 0000-0002-6140-3482
Lauren E Gloekler205740Stantec (ChemRisk), Aliso Viejo, CA, USA.
Laura H Allen205740Stantec (ChemRisk), Pittsburgh, PA, USA.
Joshua R Maskrey205740Stantec (ChemRisk), Pittsburgh, PA, USA.
Christopher Bevan458242Halogenated Solvents Industry Alliance, Inc, Arlington, VA USA.
Andrew Maier205740Stantec (ChemRisk), Cincinnati, OH, USA.
Stantec (United States) · USHalogenated Solvents Industry Alliance (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The United States Environmental Protection Agency (EPA) regulates chemical manufacture, import, processing, distribution, use, and disposal under the 2016 amended Toxic Substances Control Act (TSCA) for the purposes of protecting the public and sensitive populations-including workers-from chemical exposure risk. The publication of several TSCA risk evaluations provided a unique opportunity to evaluate the evolving regulatory approach for assessing the dermal exposure pathway in occupational settings. In this analysis, the occupational dermal exposure assessment methods employed in several TSCA risk evaluations were assessed. Specifically, a methodology review was conducted for the occupational dermal scenarios of manufacturing and feedstock use in the risk evaluations of three chlorinated organic chemicals: trichloroethylene, carbon tetrachloride, and perchloroethylene. Additionally, alternative exposure estimates were generated using the exposure model IH SkinPerm

Indexed as

Occupational ExposureCommerceHazardous SubstancesHumansRisk AssessmentUnited StatesUnited States Environmental Protection AgencyHazardous Substancesdermal exposureexposure assessmentexposure modelingregulatory risk assessmentToxic Substances Control Act

Identifiers

PMID36420912
PMCPMC9817111
OpenAlexW4309926005

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.