Evidence map›Paper›PMID 36420769›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2023

Kinetic evaluation and assessment of longitudinal changes in reference region and extracerebral [

Jessie Fanglu Fu, Cristina Lois, Justin Sanchez, J Alex Becker, Zoe B Rubinstein, Emma Thibault, Andrew N Salvatore, Hasan Sari, Michelle E Farrell, Nicolas J Guehl and 4 more

Open access · greenAbstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Off-target binding ofAnnals of nuclear medicine · 2026
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  3. Evaluation of [Acta neuropathologica communications · 2026
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  6. Quantitative Measurement of Tau Burden in a Dual-Time-Window Dynamic PET Imaging Protocol with [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
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  7. [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
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  8. Molecular neurodegeneration · 2025
    Article
  9. One-Year Longitudinal Changes in Tau Accumulation on [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Article
  10. Test-retest performance of [Imaging neuroscience (Cambridge, Mass.) · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Jessie Fanglu FuAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA.ORCID 0000-0002-4970-7811
Cristina LoisHarvard Medical School, Department of Radiology, Boston, MA, USA.
Justin SanchezGordon Center for Medical Imaging, Massachusetts General Hospital, Boston, MA, USA.
J Alex BeckerHarvard Medical School, Department of Radiology, Boston, MA, USA.
Zoe B RubinsteinGordon Center for Medical Imaging, Massachusetts General Hospital, Boston, MA, USA.
Emma ThibaultGordon Center for Medical Imaging, Massachusetts General Hospital, Boston, MA, USA.
Andrew N SalvatoreAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA.
Hasan SariAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA.
Michelle E FarrellHarvard Medical School, Department of Radiology, Boston, MA, USA.
Nicolas J GuehlHarvard Medical School, Department of Radiology, Boston, MA, USA.
Marc D NormandinHarvard Medical School, Department of Radiology, Boston, MA, USA.
Georges El FakhriHarvard Medical School, Department of Radiology, Boston, MA, USA.
Keith A JohnsonHarvard Medical School, Department of Radiology, Boston, MA, USA.
Julie C PriceAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA.
Harvard University · USGordon Center for Medical Imaging · USMassachusetts General Hospital · US

Funding

Vascular factors, physical activity, and inflammation as modulators of neurodegenerative and cognitive trajectories (Project 2)P01AG036694 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI REISA A. SPERLING · 2010 to 2026
$50.2M
Research Education ComponentP30AG062421 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI STEVEN E ARNOLD · 2019 to 2026
$36.5M
Unified Joint Statistical Reconstruction of PET & MRP41EB022544 · NIBIB · YALE UNIVERSITY · PI Georges El Fakhri · 2017 to 2026
$14.8M
Disentangling the contribution of tau to aging and ADR01AG046396 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI JOHNSON, KEITH A. · 2014 to 2018
$4.0M
Postgraduate Training Program in Medical Imaging (PTPMI)T32EB013180 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Ciprian Catana, Pedram Heidari · 2011 to 2026
$3.7M
Methods for Quantitative Neuroimaging of Tau Burden inPre-symptomatic ADR01AG076153 · NIA · YALE UNIVERSITY · PI Georges El Fakhri, Marc David Normandin · 2022 to 2026
$3.0M
Translation of tau-selective PET radiopharmaceuticals in Alzheimers patientsR01AG052414 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI PRICE, JULIE C, VASDEV, NEIL · 2018 to 2021
$2.7M
In vivo characterization of the PET pharmacokinetic properties of T807 in humansR01AG050436 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PRICE, JULIE C · 2015 to 2017
$1.6M
Gamma counter and continuous blood sampler for quantitative PET imagingS10OD018035 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI EL FAKHRI, GEORGES, NORMANDIN, MARC DAVID · 2014 to 2014
$144k
NIA NIH HHS P01 AG036694NIA NIH HHS P30 AG062421NIA NIH HHS R01 AG046396NIA NIH HHS R01 AG050436NIA NIH HHS R01 AG052414NIA NIH HHS R01 AG076153NIBIB NIH HHS P41 EB022544NIBIB NIH HHS T32 EB013180NIH HHS S10 OD018035
6 · The paper itself

Abstract

[

Indexed as

Cognitive DysfunctionCase-Control StudiesCross-Sectional StudiesHumansIsoquinolinesKineticsPositron-Emission TomographyIsoquinolinesMK-6240[18F]MK-6240extracerebral signalpositron emission tomographyreference tissue modelingtau

Identifiers

PMID36420769
PMCPMC10063833
OpenAlexW4309874651

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.