ArticlePharmacoepidemiology and drug safety2023
Validation of claims-based algorithms to identify non-live birth outcomes.
Article in Pharmacoepidemiology and drug safety, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Continuing Glucagon-Like Peptide-1 Receptor Agonists Into the First Trimester of Pregnancy and Pregnancy Outcomes : A Target Trial Emulation Study Using Claims Information.Annals of internal medicine · 2026Observational
- Evaluating and Refining Claims-Based Algorithms for Pregnancy Outcomes and Gestational Age Estimation in Korea.Journal of Korean medical science · 2026Article
- Identifying pregnancies in routinely collected health data: a scoping review of methods.BMC medical informatics and decision making · 2026Article
- Outcomes and Management of Pregnancies Screening Positive for Microdeletions 22q11.2, 15q11.2, 1p36, 4p, or 5p: A Retrospective Cohort Study.The application of clinical genetics · 2026Article
- Evaluation of gestational age by pregnancy outcomes and distribution of pregnancy-related codes in Korean claims data.Epidemiology and health · 2026Article
- Development of a Pregnancy Cohort in Commercial Insurance Claims Data: Evaluation of Deliveries Identified From Inpatient Versus Outpatient Claims.Pharmacoepidemiology and drug safety · 2025Article
- Measuring abortion in claims data: What is the state of the science?Contraception · 2025Review
- Pregnancy episodes in All of Us: harnessing multi-source data for pregnancy-related research.Journal of the American Medical Informatics Association : JAMIA · 2024Article
- Use of the Sentinel System to Examine Medical Product Use and Outcomes During Pregnancy.Drug safety · 2024Review
- Defining, measuring, and evaluating prenatal care in insurance claims data.Current epidemiology reports · 2024Article
- Identifying pregnancy episodes and estimating the last menstrual period using an administrative database in Korea: an application to patients with systemic lupus erythematosus.Epidemiology and health · 2024Article
- Using Modernized Medicaid Data to Advance Evidence-Based Improvements in Maternal Health.American journal of public health · 2023Review
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
purposePerinatal epidemiology studies using healthcare utilization databases are often restricted to live births, largely due to the lack of established algorithms to identify non-live births. The study objective was to develop and validate claims-based algorithms for the ascertainment of non-live births.
methodsUsing the Mass General Brigham Research Patient Data Registry 2000-2014, we assembled a cohort of women enrolled in Medicaid with a non-live birth. Based on ≥1 inpatient or ≥2 outpatient diagnosis/procedure codes, we identified and randomly sampled 100 potential stillbirth, spontaneous abortion, and termination cases each. For the secondary definitions, we excluded cases with codes for other pregnancy outcomes within ±5 days of the outcome of interest and relaxed the definitions for spontaneous abortion and termination by allowing cases with one outpatient diagnosis only. Cases were adjudicated based on medical chart review. We estimated the positive predictive value (PPV) for each outcome.
resultsThe PPV was 71.0% (95% CI, 61.1-79.6) for stillbirth; 79.0% (69.7-86.5) for spontaneous abortion, and 93.0% (86.1-97.1) for termination. When excluding cases with adjacent codes for other pregnancy outcomes and further relaxing the definition, the PPV increased to 80.6% (69.5-88.9) for stillbirth, 86.6% (80.5-91.3) for spontaneous abortion and 94.9% (91.1-97.4) for termination. The PPV for the composite outcome using the relaxed definition was 94.4% (92.3-96.1).
conclusionsOur findings suggest non-live birth outcomes can be identified in a valid manner in epidemiological studies based on healthcare utilization databases.
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