Evidence map›Paper›PMID 36420496›Full record

ArticleFish and shellfish immunology reports2021

Feeding with poly(I:C) induced long-term immune responses against bacterial infection in turbot (

Jing He, Zhuang Wang, Yanbo Zhao, Jin Yang, Yuanxing Zhang, Qin Liu, Dahai Yang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Fish and shellfish immunology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jing HeState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China.
Zhuang WangState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China.
Yanbo ZhaoState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China.
Jin YangState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China.
Yuanxing ZhangSouthern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai 519000, China.
Qin LiuState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China.
Dahai YangState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China.
East China University of Science and Technology · CNSouthern Marine Science and Engineering Guangdong Laboratory (Guangzhou) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Poly(I:C) is a kind of chemosynthetic double-stranded RNA (dsRNA) analogue which could act as TLR3 agonist and induce IFN production. It is widely applied in anti-virus treatment and immunoregulation, as well as vaccine adjuvant in farmed animals. However, whether poly(I:C) could activate innate immune response to defense against bacterial infection remains unclear. In this study, we established a feeding trial model with different dose of poly(I:C) in turbot larvae, then challenged with

Indexed as

Anti-oxidant stressBacterial-infectionIntestinal immune responsesPoly(I:C)turbot

Identifiers

PMID36420496
PMCPMC9680065
OpenAlexW3211742873

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.