Evidence map›Paper›PMID 36420347›Full record

ArticlePLOS digital health2022

PrimSeq: A deep learning-based pipeline to quantitate rehabilitation training.

Avinash Parnandi, Aakash Kaku, Anita Venkatesan, Natasha Pandit, Audre Wirtanen, Haresh Rajamohan, Kannan Venkataramanan, Dawn Nilsen, Carlos Fernandez-Granda, Heidi Schambra

Abstract read
In one paragraph

Article in PLOS digital health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Data-Driven Quantitation of Movement Abnormality after Stroke.Bioengineering (Basel, Switzerland) · 2023
    Article
  6. Article
  7. StrokeRehab: A Benchmark Dataset for Sub-second Action Identification.Advances in neural information processing systems · 2022
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Avinash ParnandiDepartment of Neurology, New York University Langone Health, New York, United States of America.
Aakash KakuCenter for Data Science, New York University, New York, United States of America.ORCID 0000-0002-2631-0897
Anita VenkatesanDepartment of Neurology, New York University Langone Health, New York, United States of America.
Natasha PanditDepartment of Neurology, New York University Langone Health, New York, United States of America.
Audre WirtanenDepartment of Neurology, New York University Langone Health, New York, United States of America.ORCID 0000-0003-4529-0024
Haresh RajamohanCenter for Data Science, New York University, New York, United States of America.ORCID 0000-0002-7926-9090
Kannan VenkataramananCenter for Data Science, New York University, New York, United States of America.ORCID 0000-0003-3399-3267
Dawn NilsenDepartment of Rehabilitation and Regenerative Medicine, Columbia University, New York, United States of America.ORCID 0000-0003-3976-5046
Carlos Fernandez-GrandaCenter for Data Science, New York University, New York, United States of America.ORCID 0000-0001-7039-8606
Heidi SchambraDepartment of Neurology, New York University Langone Health, New York, United States of America.ORCID 0000-0002-1886-2288

Funding

Project-005UL1TR001445 · NCATS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BREDELLA, MIRIAM ANTOINETTE, HOCHMAN, JUDITH S · 2015 to 2025
$103.5M
Quantitative Rehabilitation after StrokeK02NS104207 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SCHAMBRA, HEIDI · 2017 to 2021
$1.1M
Learning invariant representation from high- dimensional data for quantitative stroke reha R01LM013316 · NLM · NEW YORK UNIVERSITY · PI FERNANDEZ-GRANDA, CARLOS, SCHAMBRA, HEIDI · 2019 to 2022
$900k
NCATS NIH HHS UL1 TR001445NINDS NIH HHS K02 NS104207NLM NIH HHS R01 LM013316
6 · The paper itself

Abstract

Stroke rehabilitation seeks to accelerate motor recovery by training functional activities, but may have minimal impact because of insufficient training doses. In animals, training hundreds of functional motions in the first weeks after stroke can substantially boost upper extremity recovery. The optimal quantity of functional motions to boost recovery in humans is currently unknown, however, because no practical tools exist to measure them during rehabilitation training. Here, we present PrimSeq, a pipeline to classify and count functional motions trained in stroke rehabilitation. Our approach integrates wearable sensors to capture upper-body motion, a deep learning model to predict motion sequences, and an algorithm to tally motions. The trained model accurately decomposes rehabilitation activities into elemental functional motions, outperforming competitive machine learning methods. PrimSeq furthermore quantifies these motions at a fraction of the time and labor costs of human experts. We demonstrate the capabilities of PrimSeq in previously unseen stroke patients with a range of upper extremity motor impairment. We expect that our methodological advances will support the rigorous measurement required for quantitative dosing trials in stroke rehabilitation.

Identifiers

PMID36420347
PMCPMC9681023

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.