Evidence map›Paper›PMID 36420268›Full record

ReviewFrontiers in immunology2022

CD160 receptor in CLL: Current state and future avenues.

Loubna Oumeslakht, Abdel-Ilah Aziz, Armand Bensussan, Sanae Ben Mkaddem

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Aberrant Expression ofCancers · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Immune interactions in pembrolizumab (PD-1 inhibitor) cancer therapy and cardiovascular complications.American journal of physiology. Heart and circulatory physiology · 2023
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Loubna OumeslakhtInstitute of Biological Sciences, Mohammed VI Polytechnic University, Ben-Guerir, Morocco.
Abdel-Ilah AzizInstitute of Biological Sciences, Mohammed VI Polytechnic University, Ben-Guerir, Morocco.
Armand BensussanINSERM U976, Université de Paris, Hôpital Saint Louis, Paris, France.
Sanae Ben MkaddemInstitute of Biological Sciences, Mohammed VI Polytechnic University, Ben-Guerir, Morocco.
Université Mohammed VI Polytechnique · MAHôpital Saint-Louis · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD160 is a glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein expressed on cytotoxic natural killer (NK) cells and T-cell subsets. It plays a crucial role in the activation of NK-cell cytotoxicity and cytokine production. It also modulates the immune system and is involved in some pathologies, such as cancer. CD160 is abnormally expressed in B-cell chronic lymphocytic leukemia (CLL) but not expressed in normal B lymphocytes. Its expression in CLL enhances tumor cell proliferation and resistance to apoptosis. CD160 is also a potential prognostic marker for the detection of minimal residual disease (MRD) in CLL, which is important for the clinical management of CLL, the prevention of disease relapse, and the achievement of complete remission. In this review, we present an overview of CD160 and its involvement in the pathophysiology of CLL. We also discuss its use as a prognostic marker for the assessment of MRD in CLL.

Indexed as

Leukemia, Lymphocytic, Chronic, B-CellAntigens, CDGlycosylphosphatidylinositolsGPI-Linked ProteinsHumansKiller Cells, NaturalNeoplasm, ResidualReceptors, ImmunologicAntigens, CDCD160 protein, humanGlycosylphosphatidylinositolsGPI-Linked ProteinsReceptors, ImmunologicCD160chronic lymphocytic leukemiaminimal residual diseaseNK cellsprognosis

Identifiers

PMID36420268
PMCPMC9676924
OpenAlexW4308455096

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.