Evidence map›Paper›PMID 36420097›Full record

ReviewBioMed research international2022

Applications of Metallic Nanoparticles in the Skin Cancer Treatment.

Mahrokh Marzi, Mahmoud Osanloo, Mohammad Kazem Vakil, Yaser Mansoori, Abdolmajid Ghasemian, Azizallah Dehghan, Elham Zarenezhad

Abstract readReview
In one paragraph

Review in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. 3D Computational Modeling of FeNanotechnology, science and applications · 2025
    Article
  8. Review
  9. Screening of key modules and key genes in the prevention of skin cancer development based on gene volcano plot and WGCNA.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mahrokh MarziNoncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.ORCID https://orcid.org/0000-0003-3599-209X
Mahmoud OsanlooDepartment of Medical Nanotechnology, School of Advanced Technologies in Medicine, Fasa University of Medical Sciences, Fasa, Iran.ORCID https://orcid.org/0000-0002-1190-6874
Mohammad Kazem VakilDepartment of Internal Medicine, School of Medicine, Fasa University of Medical Science, Fasa, Iran.ORCID https://orcid.org/0000-0003-2234-9441
Yaser MansooriDepartment of Medical Genetics, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran.ORCID https://orcid.org/0000-0002-9101-5552
Abdolmajid GhasemianNoncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.ORCID https://orcid.org/0000-0002-1243-6341
Azizallah DehghanNoncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.ORCID https://orcid.org/0000-0002-7345-0796
Elham ZarenezhadNoncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.ORCID https://orcid.org/0000-0003-2805-1910

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin cancer is one of leading cancers globally, divided into two major categories including melanoma and nonmelanoma. Skin cancer is a global concern with an increasing trend, hence novel therapies are essential. The local treatment strategies play a key role in skin cancer therapy. Nanoparticles (NPs) exert potential applications in medicine with huge advantages and have the ability to overcome common chemotherapy problems. Recently, NPs have been used in nanomedicine as promising drug delivery systems. They can enhance the solubility of poorly water-soluble drugs, improve pharmacokinetic properties, modify bioavailability, and reduce drug metabolism. The high-efficient, nontoxic, low-cost, and specific cancer therapy is a promising goal, which can be achieved by the development of nanotechnology. Metallic NPs (MNPs) can act as important platforms. MNPs development seeks to enhance the therapeutic efficiency of medicines through site specificity, prevention of multidrug resistance, and effective delivery of therapeutic factors. MNPs are used as potential arms in the case of cancer recognition, such as Magnetic Resonance Imaging (MRI) and colloidal mediators for magnetic hyperthermia of cancer. The applications of MNPs in the cancer treatment studies are mostly due to their potential to carry a large dose of drug, resulting in a high concentration of anticancer drugs at the target site. Therefore, off-target toxicity and suffering side effects caused by high concentration of the drug in other parts of the body are avoided. MNPs have been applied as drug carriers for the of improvement of skin cancer treatment and drug delivery. The development of MNPs improves the results of many cancer treatments. Different types of NPs, such as inorganic and organic NPs have been investigated

Indexed as

Magnetite NanoparticlesSkin NeoplasmsAdministration, CutaneousDrug CarriersDrug Delivery SystemsHumansDrug CarriersMagnetite Nanoparticles

Identifiers

PMID36420097
PMCPMC9678447

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.