Evidence map›Paper›PMID 36420077›Full record

ArticleOncology letters2022

Expression level comparison of marker genes related to early embryonic development and tumor growth.

Qiu-Chen Cai, Da-Lun Li, Ying Zhang, Yun-Yi Liu, Pei Fang, Si-Qin Zheng, Yue-Yan Zhang, Ya-Kun Yang, Chun Hou, Cheng-Wei Gao and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Qiu-Chen CaiSchool of Life Sciences, Yunnan University, Kunming, Yunnan 650500, P.R. China.
Da-Lun LiSchool of Life Sciences, Yunnan University, Kunming, Yunnan 650500, P.R. China.
Ying ZhangSchool of Life Sciences, Yunnan University, Kunming, Yunnan 650500, P.R. China.
Yun-Yi LiuSchool of Life Sciences, Yunnan University, Kunming, Yunnan 650500, P.R. China.
Pei FangSchool of Life Sciences, Yunnan University, Kunming, Yunnan 650500, P.R. China.
Si-Qin ZhengSchool of Life Sciences, Yunnan University, Kunming, Yunnan 650500, P.R. China.
Yue-Yan ZhangSchool of Life Sciences, Yunnan University, Kunming, Yunnan 650500, P.R. China.
Ya-Kun YangSchool of Life Sciences, Yunnan University, Kunming, Yunnan 650500, P.R. China.
Chun HouSchool of Ecology and Environmental Science, Yunnan University, Kunming, Yunnan 650500, P.R. China.
Cheng-Wei GaoSchool of Chemical Science and Technology, Yunnan University, Kunming, Yunnan 650500, P.R. China.
Qi-Shun ZhuSchool of Life Sciences, Yunnan University, Kunming, Yunnan 650500, P.R. China.
Chuan-Hai CaoTaneja College of Pharmacy, University of South Florida, Tampa, FL 33612, USA.
Yunnan University · CNUniversity of South Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In tumor research, the occurrence and origin of tumors are the fundamental problems. In the 1970s, the basic discussion of the developmental biology problem of tumors was proposed, and it was believed that tumorigenesis is closely related to developmental biology. Tumors are abnormal biological structures in organisms, and their biological behavior is very similar to that of the early embryo. Many tumor-related genes also serve regulatory roles in the normal development and differentiation of embryos. However, it remains unclear whether gene expression in early embryos has any similarities with tumor cells. In this study, to compare the similarities and differences in gene expression between early embryos and tumor cells, reverse transcription-quantitative PCR was conducted to determine and compare the relative expression levels of nine tumor-related genes in the brain glioma cell line, T98G, and in the early embryo of

Indexed as

developmental biologyembryoevolutionary biologytumor

Identifiers

PMID36420077
PMCPMC9647793
OpenAlexW4307547038

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.