Evidence map›Paper›PMID 36420056›Full record

ArticleMaterials today. Bio2022

Natural blood plasma-based hydrogels as tumor vaccines delivery systems to enhance biomimetic recruitment of antigen presenting cells for tumor immunotherapy.

Linghong Huang, Sufen Peng, Zonghua Liu, Juncheng Zhang, Ning Liu, Jiansheng Lin

Open access · goldAbstract read
In one paragraph

Article in Materials today. Bio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Linghong HuangDepartment of Biomedical Engineering, Jinan University, Guangzhou, 510632, China.
Sufen PengDepartment of Biomedical Engineering, Jinan University, Guangzhou, 510632, China.
Zonghua LiuDepartment of Biomedical Engineering, Jinan University, Guangzhou, 510632, China.
Juncheng ZhangDepartment of Bone and Joint Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, 510632, China.
Ning LiuDepartment of Bone and Joint Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, 510632, China.
Jiansheng LinDepartment of Anatomy, Hunan University of Chinese Medicine, Changsha, 410208, China.
Jinan University · CNFirst Affiliated Hospital of Jinan University · CNHunan University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor vaccines can inhibit or eliminate tumors by vaccinating hosts with tumor antigens to activate antigen-specific immune responses and have gained wild attention. However, their clinical application efficacy is often comprised due to the low safety and poor efficiency of vaccine adjuvants/carriers. Specifically, the adjuvants/carriers usually could not efficiently recruit antigen presenting cells (APCs) to capture the vaccines or directly damage these cells. Therefore, ideal tumor vaccine adjuvants/carriers should effectively recruit APCs and be friendly to the cells for well keeping their bio-functions. In this work, injectable natural blood plasma hydrogel was used for the first time to encapsulate tumor antigens and adjuvant (Mn

Indexed as

APCs recruitmentBlood plasma hydrogelTumor immunotherapyTumor vaccines

Identifiers

PMID36420056
PMCPMC9677221
OpenAlexW4309683039

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.