ArticleBrain communications2022
Intrinsic brain functional connectivity patterns in alcohol use disorder.
Article in Brain communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Stress and alcohol impact network states involved in emotional processing: relevance of comorbid AUD and psychiatric illnesses.Psychopharmacology · 2026Pooled it
- Relating Functional Connectivity and Alcohol Use Disorder: A Systematic Review and Derivation of Relevance Maps for Regions and Connections.Human brain mapping · 2025Pooled it
- Using deep learning to identify brain networks mediating cognitive and motor impairments in alcohol use disorder.Translational psychiatry · 2026Article
- Introducing Structural Reliance: A New Method to Assess Structure-Function Coupling in the Brain.Human brain mapping · 2026Article
- Social closeness and reward sensitivity enhance corticostriatal function during experiences of shared rewards.Biological psychology · 2026Article
- Alcohol Cues Elicit Differences in Brain Activation Patterns of Abstinent Men and Women with Alcohol Use Disorders.Neuropsychiatric disease and treatment · 2026Article
- Abstinence Alters Triple Network Dynamics in Moderate-to-Heavy Drinkers.Human brain mapping · 2025Article
- Alcohol cue processing alters delta-band functional connectivity and theta-band network topology in alcohol use disorder: a task-based EEG study.BMC psychiatry · 2025Article
- Narcissistic and Antisocial Personality Traits Are Both Encoded in the Triple Network: Connectomics Evidence.Psychophysiology · 2025Article
- Social Closeness and Reward Sensitivity Enhance Corticostriatal Function during Experiences of Shared Rewards.bioRxiv : the preprint server for biology · 2025Article
- Altered resting-state network connectivity in internet gaming disorder.Annals of general psychiatry · 2025Article
- Neural correlates of executive dysfunction in alcohol use disorder: preliminary evidence fromFrontiers in psychology · 2025Article
- Reduced brain network segregation in alcohol use disorder: Associations with neurocognition.Addiction biology · 2024Article
- Triple network resting-state functional connectivity patterns of alcohol heavy drinking.Alcohol and alcoholism (Oxford, Oxfordshire) · 2024Article
- Compensation patterns and altered functional connectivity in alcohol use disorder with and without Korsakoff's syndrome.Brain communications · 2024Article
- Differences in Brain Network Topology Based on Alcohol Use History in Adolescents.Brain sciences · 2023Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
Alcohol use disorder is associated with damaging effects to the brain. This study aimed to examine differences in static and dynamic intrinsic functional connectivity patterns in individuals with a history of alcohol use disorder in comparison to those with no history of alcohol abuse. A total of 55 participants consisting of 23 patients and 32 control individuals underwent neuropsychological assessments and resting-state functional magnetic resonance imaging on a 3 Tesla MRI scanner. Differences in functional connectivity between the two groups were determined using static and dynamic independent component analysis. Differences in static functional connectivity between the two groups were identified in the default mode network, attention network, frontoparietal network, frontal cortical network and cerebellar network. Furthermore, the analyses revealed specific differences in the dynamic temporal characteristics of functional connectivity between the two groups of participants, in a cluster involving key regions in reward, sensorimotor and frontal cortical functional networks, with some connections correlating with the length of sobriety and some others with the severity of drinking. The findings altogether suggest dysregulation in the intrinsic connectivity of cortico-basal ganglia-thalamo-cortical loops that may reflect persistent alcohol use disorder-related network abnormalities, compensatory recovery-related processes whereby additional neural resources are recruited to achieve normal levels of performance, or a predisposition toward developing alcohol use disorder.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.