Evidence map›Paper›PMID 36419779›Full record

ArticleFish and shellfish immunology reports2020

Protein kinase-like ER kinase (PERK) regulates autophagy of hemocytes in antiviral immunity of Pacific oyster

Shujing Liu, Weilin Wang, Yu Liu, Wanqing Cao, Pei Yuan, Jiaxin Li, Xiaorui Song, Lingling Wang, Linsheng Song

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Fish and shellfish immunology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Shujing LiuLiaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian 116023, China.
Weilin WangLiaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian 116023, China.
Yu LiuLiaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian 116023, China.
Wanqing CaoLiaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian 116023, China.
Pei YuanLiaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian 116023, China.
Jiaxin LiLiaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian 116023, China.
Xiaorui SongLiaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian 116023, China.
Lingling WangLiaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian 116023, China.
Linsheng SongLiaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian 116023, China.
Dalian Ocean University · CNQingdao National Laboratory for Marine Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The maintenance of cellular homeostasis is an important process for successful immune defense against pathogenic invading, in which unfolded protein response (UPR) pathway regulates endoplasmic reticulum (ER) homeostasis upon exposure to environmental changes. Protein kinase-like ER kinase (PERK) is an important ER stress sensor to be activated during the UPR to regulate cells homeostasis. In the present study, one PERK homologue was identified from Pacific oyster

Indexed as

AutophagyCrassostrea gigaspoly(I: C)Protein kinase-like endoplasmic reticulum kinaseUnfolded protein response

Identifiers

PMID36419779
PMCPMC9680061
OpenAlexW3112788069

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.